4-(Aminomethyl)piperidine - ≥98%(GC) , CAS No.7144-05-0

CAS: 7144-05-0 Cat. No.: A136022 Molecular Weight: 114.19 Beilstein Registry Number: 471185 EC Number: 230-446-3

GRADE & PURITY ≥98%(GC)

Synonyms

DTXSID8064569 | NSC62826 | NSC-62826 | 4-Piperidylmethylamine | (piperidin-4-yl)methanamine | FT-0617581 | 1-(piperidin-4-yl)methanamine | TS-01585 | piperidin-4-ylmethylamine | 4-AMP

Storage

Argon charged,Room temperature

Shipped In

Normal

Overview

Reactant: Evaulated as a small molecule inhibitor of CD4-gp120 binding Reagent Involved in solvothermal preparation of germanium oxide hydroxide 3D net zeotype Involved in zeolite synthesis Coupling agent for adhesive systems

Specifications

Synonyms

DTXSID8064569 | NSC62826 | NSC-62826 | 4-Piperidylmethylamine | (piperidin-4-yl)methanamine | FT-0617581 | 1-(piperidin-4-yl)methanamine | TS-01585 | piperidin-4-ylmethylamine | 4-AMP

Specifications & Purity

≥98%(GC)

Storage

Argon charged, Room temperature

Shipped In

Normal

Purity

≥98%(GC)

Names and Identifiers

• Pubchem Sid: 488182830
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488182830
• Canonical Smiles: C1CNCCC1CN
• IUPAC Name: piperidin-4-ylmethanamine
• InChIKey: LTEKQAPRXFBRNN-UHFFFAOYSA-N
• INCHI: 1S/C6H14N2/c7-5-6-1-3-8-4-2-6/h6,8H,1-5,7H2
• Isomeric SMILES: C1CNCCC1CN
• WGK Germany: 3
• Molecular Weight: 114.19
• Beilstein: 471185
• Reaxy-Rn: 471185
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=471185&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Piperidines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Piperidines
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Piperidines
• Alternative Parents: Dialkylamines Azacyclic compounds Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Piperidine - Azacycle - Secondary amine - Secondary aliphatic amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Primary aliphatic amine - Amine - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as piperidines. These are compounds containing a piperidine ring, which is a saturated aliphatic six-member ring with one nitrogen atom and five carbon atoms.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water.
• Sensitivity: air sensitive
• Refractive Index: 1.49
• Flash Point(°F): 172.4 °F
• Flash Point(°C): 79℃
• Boil Point(°C): 200 °C
• Melt Point(°C): 25°C
• Molecular Weight: 114.190 g/mol
• XLogP3: -0.400
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 114.116 Da
• Monoisotopic Mass: 114.116 Da
• Topological Polar Surface Area: 38.100 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 57.500
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

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2. Yan Wang, Song Wang, Zhiyan Sui, Yiman Gu, Yanchao Zhang, Jian Gao, Yijia Lei, Jialin Zhao, Na Li, JingYi Wu, Zhe Wang.  (2024)  “Fishbone” Design of Amino/N-Spirocyclic Cations toward High-Performance Poly(triphenylene piperidine) Anion-Exchange Membranes for Fuel Cells.  ACS Applied Materials & Interfaces,      [PMID:38207002] [10.1021/acsami.3c16029]

3. Quanliang Mao, Mengyin Gu, Chengyuan Hong, Huiying Wang, Xinzhong Ruan, Zhusheng Liu, Bo Yuan, Mengting Xu, Chen Dong, Lei Mou, Xiang Gao, Guangyu Tang, Tianxiang Chen, Aiguo Wu, Yuning Pan.  (2024)  A Contrast-Enhanced Tri-Modal MRI Technique for High-Performance Hypoxia Imaging of Breast Cancer.  Small,      [PMID:38366271] [10.1002/smll.202308850]

4. Sun Zeyuan, Gu Ningxia, Zha Leying, Ning Lei, Du Pingfan, Shi Chenyang, Song Lixin, Xiong Jie.  (2024)  Air-processed 2D/3D perovskite solar cell achieve high-efficient and stable performance via graded interface engineering.  MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING,      [PMID:] [10.1016/j.mssp.2024.108185]

5. Xuemei Zeng, Jianxiang Feng, Yulin He, Siyu Cao, Cheng Zhou, Kangqi Li, Jinjing Tan, Shuyi Chen, Yong Xia, Yuejun Liu, Pu Shi, Jin Zhu.  (2024)  Bio-based and effective: Cardanol-piperidine derivatives for enhanced polypropylene resistance against thermo- and photo-oxidative aging.  JOURNAL OF VINYL & ADDITIVE TECHNOLOGY,      [PMID:] [10.1002/vnl.22113]

6. Shihai You, Lemei Long, Chenhao Deng, Haiqing Zhong, Qianwen Guan, Jiasheng Xie, Zheng Zhou, Panpan Yu, Weiqing Yang.  (2025)  High-Sensitivity and Stable X-Ray Detection with Low Detection Limit Enabled by a Short-Interlayer-Spaced 2D Bilayer Dion-Jacobson Perovskite.  Advanced Optical Materials,      [PMID:] [10.1002/adom.202502700]