4-Aminostyrene（P4VA） - ≥95%(T) , CAS No.1520-21-4

CAS: 1520-21-4 Cat. No.: A151485 Molecular Weight: 119.17 EC Number: 216-185-8

GRADE & PURITY ≥95%(T)

Synonyms

p-Aminostyrene | 4-vinylphenylamine | P4VA

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

4-Vinylaniline (4-VAn) is a primary amine surfactant.
4-VAn undergoes graft copolymerization with poly(tetrafluoroethylene) (PTFE) and Si surface, followed by oxidative copolymerization with aniline. Thus, it renders PTFE and Si surface conductive.4-VAn is coupled with hydrogen terminated Si surfaces for electroless metal and synthetic metal deposition.Palladium(II) schiff base complexes derived from Allylamine and vinylaniline has been reported. It also acts as a second surfactant for coating nanomagnetic particles. It is used in functionalization of single-walled carbon nanotube through solvent free functionalization.

General description
4-Vinylaniline is a vinyl-substituted aromatic amine that is widely used as a crosslinking agent in the production of resins, adhesives, and coatings, enhancing their mechanical properties and chemical resistance. It can be polymerized by methods like radical polymerization, cationic polymerization, or oxidative polymerization to form poly(4-vinylaniline) or P4VA. 4- Vinylaniline can be selectively polymerized or chemically modified to respond to specific analytes or stimuli, allowing the development of conductive polymers for biosensors.
Application
4-Vinylaniline can be used as:
A monomer to prepare electrically conductive polyvinylaniline/polyaniline (PVAN/PANI) bilayer for surface modification of bacterial cellulose (BC) nanofibril network. This material can be utilized as an electrochemical biosensor for nerve regenerative medicine.
To functionalize carbon nanodots for in vivo fluorometric biosensors, for the detection of mercury and cysteine.
As a precursor to prepare conductive and biocompatible hydrogels forwound healing applications.

Specifications

Synonyms

p-Aminostyrene | 4-vinylphenylamine | P4VA

Specifications & Purity

≥95%(T)

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%(T)

Names and Identifiers

• Canonical Smiles: C=CC1=CC=C(C=C1)N
• IUPAC Name: 4-ethenylaniline
• InChIKey: LBSXSAXOLABXMF-UHFFFAOYSA-N
• INCHI: 1S/C8H9N/c1-2-7-3-5-8(9)6-4-7/h2-6H,1,9H2
• Isomeric SMILES: C=CC1=CC=C(C=C1)N
• Molecular Weight: 119.17
• Reaxy-Rn: 2204173
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2204173&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Styrenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Styrenes
• Intermediate Tree Nodes: Not available
• Direct Parent: Styrenes
• Alternative Parents: Aniline and substituted anilines Primary amines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Aniline or substituted anilines - Styrene - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as styrenes. These are organic compounds containing an ethenylbenzene moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in Methanol,Benzene,Acetone
• Sensitivity: light & heat & air sensitive
• Refractive Index: n20/D 1.626
• Boil Point(°C): 213-214 °C
• Melt Point(°C): 21 °C
• Molecular Weight: 119.160 g/mol
• XLogP3: 1.800
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 119.073 Da
• Monoisotopic Mass: 119.073 Da
• Topological Polar Surface Area: 26.000 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 90.700
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

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2. Ye Wei, Xuejie Yu, Ping Wang, Yuanyuan Yu, Jiugang Yuan, Qiang Wang, Xuerong Fan.  (2021)  Antibacterial Functionalization of Silk Fabrics following in Situ Coloring with Diazo Salts.  Journal of Natural Fibers,      [PMID:] [10.1080/15440478.2019.1701605]

3. Yujie Wang, Jiaying Liu, Yongbo Cui, Meng Liu, Wenxia Chen, Wei Wei, Haifeng Lu, Dongyun Han.  (2025)  Amorphous CoS polyhedron endow efficient electrocatalytic semi-hydrogenation of acetylene.  Materials Today Communications,      [PMID:] [10.1016/j.mtcomm.2025.112431]