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· · COA & SDS available for every product · Same-day shipping on in-stock items (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol , Tyrosine-protein kinase JAK2 inhibitor, CAS No.1241914-87-3, Tyrosine-protein kinase JAK2 inhibitor
Synonyms
DB12535 | (4-fluorophenyl)-[4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]methanol | E7YVO9NSJ9 | 2-QUINAZOLINEMETHANOL, .ALPHA.-(4-FLUOROPHENYL)-4-((5-METHYL-1H-PYRAZOL-3-YL)AMINO)- | CHEMBL3545241 | AC-430 | 4-Fluorophenyl(4-((5-Methyl-1H-Pyrazol-3
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Why this grade for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
DB12535 | (4-fluorophenyl)-[4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]methanol | E7YVO9NSJ9 | 2-QUINAZOLINEMETHANOL, .ALPHA.-(4-FLUOROPHENYL)-4-((5-METHYL-1H-PYRAZOL-3-YL)AMINO)- | CHEMBL3545241 | AC-430 | 4-Fluorophenyl(4-((5-Methyl-1H-Pyrazol-3
Mechanism of action
Tyrosine-protein kinase JAK2 inhibitor
Product Properties Names and Identifiers Canonical Smiles CC1=CC(=NN1)NC2=NC(=NC3=CC=CC=C32)C(C4=CC=C(C=C4)F)O IUPAC Name (4-fluorophenyl)-[4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]methanol InChIKey DCRWIATZWHLIPN-UHFFFAOYSA-N INCHI 1S/C19H16FN5O/c1-11-10-16(25-24-11)22-18-14-4-2-3-5-15(14)21-19(23-18)17(26)12-6-8-13(20)9-7-12/h2-10,17,26H,1H3,(H2,21,22,23,24,25) Isomeric SMILES CC1=CC(=NN1)NC2=NC(=NC3=CC=CC=C32)C(C4=CC=C(C=C4)F)O PubChem CID 46892373 Molecular Weight 349.4
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Diazanaphthalenes Subclass Benzodiazines Intermediate Tree Nodes Quinazolines Direct Parent Quinazolinamines Alternative Parents Fluorobenzenes Aminopyrimidines and derivatives Imidolactams Aryl fluorides Pyrazoles Heteroaromatic compounds Secondary alcohols Secondary amines Azacyclic compounds Organofluorides Hydrocarbon derivatives Aromatic alcohols Molecular Framework Aromatic heteropolycyclic compounds Substituents Quinazolinamine - Aminopyrimidine - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Imidolactam - Benzenoid - Pyrimidine - Monocyclic benzene moiety - Heteroaromatic compound - Azole - Pyrazole - Secondary alcohol - Azacycle - Secondary amine - Alcohol - Organohalogen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Aromatic alcohol - Hydrocarbon derivative - Organic oxygen compound - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as quinazolinamines. These are heterocyclic aromatic compounds containing a quianazoline moiety substituted by one or more amine groups. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 349.400 g/mol XLogP3 3.400 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 4 Exact Mass 349.134 Da Monoisotopic Mass 349.134 Da Topological Polar Surface Area 86.700 Ų Heavy Atom Count 26 Formal Charge 0 Complexity 461.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 1 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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