4-Hydroxynonenal (4-HNE) - Moligand™, 10mM in DMSO , Activator of TRPA1, CAS No.75899-68-2, Activator of TRPA1

CAS: 75899-68-2 Cat. No.: H425859 Molecular Weight: 156.22

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

4-hydroxy Nonenal;4-Hydroxy-2-nonenal;4-hydroxynon-2-enal

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.

Specifications

Synonyms

4-hydroxy Nonenal;4-Hydroxy-2-nonenal;4-hydroxynon-2-enal

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

Marker of lipid peroxidation. Prevents NF-κB activation and TNF expression by inhibiting IκB phosphorylation. Range of biological effects such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. Active in vivo .

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

ACTIVATOR

Mechanism of action

Activator of TRPA1

Names and Identifiers

• Isomeric SMILES: CCCCCC(/C=C/C=O)O
• Molecular Weight: 156.22
• Reaxy-Rn: 1931593
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1931593&ln=

Associated Targets(Human)

TRPA1 Tclin Transient receptor potential cation channel subfamily A member 1 (1 Activities)

Discover Target: TRPA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemical and Physical Properties

• Sensitivity: air and light sensitive