4-Methoxyphenethylamine - ≥98% , CAS No.55-81-2

CAS: 55-81-2 Cat. No.: M106422 Molecular Weight: 151.21 Beilstein Registry Number: 508967 EC Number: 200-245-5

GRADE & PURITY ≥98%

Synonyms

4-methoxybenzenethanamine | SCHEMBL4634 | 4-Methoxy-benzeneethanamine | PHENETHYLAMINE, p-METHOXY- | USAF EL-52 | NSC 43687 | SY001720 | ZHH | 4-methoxylphenylethylamine | AMY41549 | NCGC00163353-01 | WLN: Z2R DO1 | doi:10.14272/LTPVSOCPYWDIFU-UHFFFAOYSA-

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

4-Methoxyphenethylamine inhibits the monoamine oxidase-catalyzed deamination of both tyramine and tryptamine
An inhibitor of the deamination of tyramine and tryptamine

Specifications

Synonyms

4-methoxybenzenethanamine | SCHEMBL4634 | 4-Methoxy-benzeneethanamine | PHENETHYLAMINE, p-METHOXY- | USAF EL-52 | NSC 43687 | SY001720 | ZHH | 4-methoxylphenylethylamine | AMY41549 | NCGC00163353-01 | WLN: Z2R DO1 | doi:10.14272/LTPVSOCPYWDIFU-UHFFFAOYSA-

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

2-(4-Methoxyphenyl)ethylamine is a common synthetic precursor and inhibitor of the monoamine-oxidase catalyzed deamination of both tyramine and tryptamine.

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: COC1=CC=C(C=C1)CCN
• IUPAC Name: 2-(4-methoxyphenyl)ethanamine
• InChIKey: LTPVSOCPYWDIFU-UHFFFAOYSA-N
• INCHI: 1S/C9H13NO/c1-11-9-4-2-8(3-5-9)6-7-10/h2-5H,6-7,10H2,1H3
• Isomeric SMILES: COC1=CC=C(C=C1)CCN
• WGK Germany: 3
• RTECS: SH7875000
• UN Number: 2735
• Molecular Weight: 151.21
• Beilstein: 508967
• Reaxy-Rn: 508967
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=508967&ln=

Associated Targets(Human)

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Taar1 Trace amine-associated receptor 1 (899 Activities)

Discover Target: Taar1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Light & Air Sensitive
• Refractive Index: 1.538
• Boil Point(°C): 138 °C/18 mmHg
• Molecular Weight: 151.210 g/mol
• XLogP3: 1.600
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 151.1 Da
• Monoisotopic Mass: 151.1 Da
• Topological Polar Surface Area: 35.300 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 97.700
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Yunxuan Cao, Xingfu Wang, Juanjuan Sun, Ling Xiang, Dongyang Li, Longfei He, Fangliang Gao, Changsong Chen, Shuti Li.  (2023)  Synergistic Ion-Anchoring Passivation for Perovskite Solar Cells with Efficiency Exceeding 24% and Ultra-Ambient Stability.  ACS Applied Materials & Interfaces,      [PMID:37556164] [10.1021/acsami.3c07422]

2. Lei Ge, Yang Wang, Xiang Gao, Min Li, Runqi Zhang, Siyu Liu, Yihang Yu, Mingguang Li, Ligang Xu, Ye Tao, Runfeng Chen, Wenzhen Lv.  (2022)  Stimulating Efficient and Stable Ultralong Phosphorescence of 2D Perovskites by Dual-Mode Triplet Exciton Stabilization.  CHEMISTRY OF MATERIALS,      [PMID:] [10.1021/acs.chemmater.2c01501]

3. Jingjing Zhu, Huaqiang Chen, Lan Wang, Engang Fu, Jianping Wu, Qilei Zhang, Lirong Yang, Gang Xu.  (2021)  High-efficient dynamic kinetic resolution of amines with a core-shell hollow mesoporous MIL-101@Pd@ZIF-8 nanocatalyst and lipase.  MICROPOROUS AND MESOPOROUS MATERIALS,      [PMID:] [10.1016/j.micromeso.2021.111490]

4. Wenzhen Lv, Yebo Cai, Yang Wang, Chengxi Sun, Xiangyu Chen, Siyu Liu, Chaofei Han, Ying Tang, Ligang Xu, Dongqing Lin, Runfeng Chen.  (2024)  Organic Room-Temperature Phosphorescence of Layered Organic Ammonium Chloride via Layer-By-Layer Assembly.  CHEMISTRY OF MATERIALS,      [PMID:] [10.1021/acs.chemmater.4c01352]