Determine the necessary mass, volume, or concentration for preparing a solution.
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Application:
4-(Methylamino)pyridine can be used:
To functionalize hypercrosslinked emulsion-templated porous polymers (polyHIPE) to form a highly efficient heterogeneous nucleophilic catalyst for the acylation of a tertiary alcohol.
As a reactant to synthesize 4-(N-allyl-N-methylamino)pyridine, which is employed as an intermediate to prepare DMAP/SBA-15 supported catalyst for the synthesis of propylene carbonate.
To prepare 5-azaoxindoles via homolytic aromatic substitution;
4-(Methylamino)pyridine was employed as efficient nucleophilic catalyst during the preparation of ultra-high surface area emulsion templated porous polymers
| Pubchem Sid | 488187713 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488187713 |
| Canonical Smiles | CNC1=CC=NC=C1 |
| IUPAC Name | N-methylpyridin-4-amine |
| InChIKey | LSCYTCMNCWMCQE-UHFFFAOYSA-N |
| INCHI | 1S/C6H8N2/c1-7-6-2-4-8-5-3-6/h2-5H,1H3,(H,7,8) |
| Isomeric SMILES | CNC1=CC=NC=C1 |
| WGK Germany | 3 |
| Molecular Weight | 108.14 |
| Reaxy-Rn | 108213 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=108213&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Pyridines and derivatives |
| Subclass | Aminopyridines and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Aminopyridines and derivatives |
| Alternative Parents | Secondary alkylarylamines Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Secondary aliphatic/aromatic amine - Aminopyridine - Heteroaromatic compound - Azacycle - Secondary amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as aminopyridines and derivatives. These are organic heterocyclic compounds containing an amino group attached to a pyridine ring. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 03, 2025 | M119978 | |
| Certificate of Analysis | Apr 01, 2024 | M119978 | |
| Certificate of Analysis | Apr 01, 2024 | M119978 | |
| Certificate of Analysis | Apr 01, 2024 | M119978 | |
| Certificate of Analysis | Apr 01, 2024 | M119978 | |
| Certificate of Analysis | Apr 01, 2024 | M119978 | |
| Certificate of Analysis | Jul 07, 2023 | M119978 | |
| Certificate of Analysis | Mar 13, 2023 | M119978 | |
| Certificate of Analysis | Feb 07, 2023 | M119978 | |
| Certificate of Analysis | Jul 14, 2021 | M119978 |
| Solubility | Soluble in Methanol |
|---|---|
| Sensitivity | air sensitive |
| Boil Point(°C) | 100°C/0.1mmHg |
| Melt Point(°C) | 127°C |
| Molecular Weight | 108.140 g/mol |
| XLogP3 | 0.800 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 108.069 Da |
| Monoisotopic Mass | 108.069 Da |
| Topological Polar Surface Area | 24.900 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 57.500 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Xiankun Wu, Chang-an Xu, Mangeng Lu, Kunxin Wang, Zhao Li, Hui Yang. (2022) Preparation and characterization of high temperature resistant thermosetting polyphenylene ether resin. JOURNAL OF APPLIED POLYMER SCIENCE, 139 (39): (e52858). [PMID:] [10.1002/app.52858] |
| 2. Xiaojie Li, Hui Shi, Yan Cui, Kai Pan, Wei Wei, Xiaoya Liu. (2020) Dextran-caffeic acid/tetraaniline composite coatings for simultaneous improvement of cytocompatibility and corrosion resistance of magnesium alloy. PROGRESS IN ORGANIC COATINGS, [PMID:] [10.1016/j.porgcoat.2020.105928] |
| 3. Pengju Zhang, You Li, Yaohui Tang, Hui Shen, Jiankai Li, Zhengfang Yi, Qinfei Ke, He Xu. (2020) Copper-Based Metal–Organic Framework as a Controllable Nitric Oxide-Releasing Vehicle for Enhanced Diabetic Wound Healing. ACS Applied Materials & Interfaces, [PMID:32216291] [10.1021/acsami.0c01792] |
| 4. Dan Chen, Binglin Li, Bin Li, Xiaoli Zhang, Longhui Wei, Wenwen Zheng. (2019) Synthesis of vitamin E succinate catalyzed by nano-SiO2 immobilized DMAP derivative in mixed solvent system. Green Processing and Synthesis, 8 (1): (667-676). [PMID:] [10.1515/gps-2019-0037] |
| 5. Li Bin, Chen Dan, Zhang Xiaoli, Dong Wenbo, Zhao Binxia. (2018) A convenient method to immobilize 4-dimethylaminopyridine on silica gel as a heterogeneous nucleophilic catalyst for acylation. CHEMICAL PAPERS, 72 (6): (1339-1345). [PMID:] [10.1007/s11696-018-0381-2] |
| 6. Yaya Wang, Qi Zhang, Yingying Man, Xiaobin Wu, Yingchun Yin, Xiufang Liu, Hongbing Song, Xin Jin. (2024) Functionally enhanced polyether-bridged amidopyridinium dicationic ionic liquids for highly efficient and sustainable fixation of CO2 to cyclic carbonates. FUEL, [PMID:] [10.1016/j.fuel.2024.132301] |