6-HydroxyDopamineHydrochloride - Moligand™, ≥97% , CAS No.28094-15-7

CAS: 28094-15-7 Cat. No.: H135753 Molecular Weight: 205.64 Beilstein Registry Number: 4274007 EC Number: 248-837-2

2 Citations COA

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6-HydroxyDopamineHydrochloride - Moligand™, ≥97% CAS No(28094-15-7) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? ≥97%

Synonyms

Oxidopamine (hydrochloride) | 2,4,5-Trihydroxyphenethylamine hydrochloride | Oxidopamine hydrochloride | 6-OHDA

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Documents & Articles Citations of This Product References Solution Calculators Reviews

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Why this grade

Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

6-Hydroxydopamine hydrochloride is a selective catecholaminergic neurotoxin. 6-Hydroxydopamine hydrochloride depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons. Causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats, producing an animal model of Parkinson's disease.
A selective catecholaminergic neurotoxin.

Specifications

Synonyms

Oxidopamine (hydrochloride) | 2, 4, 5-Trihydroxyphenethylamine hydrochloride | Oxidopamine hydrochloride | 6-OHDA

Specifications & Purity

Moligand™, ≥97%

Biochemical and Physiological Mechanisms

Neurotoxin that destroys catecholaminergic terminals.

Storage

Store at 2-8°C, Protected from light, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥97%

Names and Identifiers

Canonical Smiles	C1=C(C(=CC(=C1O)O)O)CCN.Cl
IUPAC Name	5-(2-aminoethyl)benzene-1,2,4-triol;hydrochloride
InChIKey	QLMRJHFAGVFUAC-UHFFFAOYSA-N
INCHI	1S/C8H11NO3.ClH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
Isomeric SMILES	C1=C(C(=CC(=C1O)O)O)CCN.Cl
WGK Germany	3
RTECS	DC4650000
Molecular Weight	205.64
Beilstein	4274007
Reaxy-Rn	4274007
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4274007&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Phenols
    - Subclass Benzenediols
      - Level5 Catechols
        Level6 Catecholamines and derivatives

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Phenols
Subclass	Benzenediols
Intermediate Tree Nodes	Catechols
Direct Parent	Catecholamines and derivatives
Alternative Parents	Phenethylamines Hydroxyquinols and derivatives 2-arylethylamines Aralkylamines 1-hydroxy-2-unsubstituted benzenoids Polyols Organopnictogen compounds Monoalkylamines Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Catecholamine - Hydroxyquinol derivative - Phenethylamine - 2-arylethylamine - 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Monocyclic benzene moiety - Polyol - Primary amine - Amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrochloride - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as catecholamines and derivatives. These are compounds containing 4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] or a derivative thereof formed by substitution.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)

Discover Target: PLK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)

Discover Target: ALOX15

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)

Discover Target: PIN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	Date	Item
D2601416	Certificate of Analysis	Apr 03, 2026	H135753
D2601415	Certificate of Analysis	Apr 03, 2026	H135753
D2601414	Certificate of Analysis	Apr 03, 2026	H135753
D2601412	Certificate of Analysis	Apr 03, 2026	H135753
D2601411	Certificate of Analysis	Apr 03, 2026	H135753
E2421155	Certificate of Analysis	Mar 11, 2026	H135753
A2424128	Certificate of Analysis	Oct 29, 2025	H135753
A2424139	Certificate of Analysis	Oct 29, 2025	H135753
A2424134	Certificate of Analysis	Oct 29, 2025	H135753
A2424130	Certificate of Analysis	Oct 29, 2025	H135753
H2528291	Certificate of Analysis	Sep 09, 2025	H135753
H2528292	Certificate of Analysis	Sep 09, 2025	H135753
H2528293	Certificate of Analysis	Sep 09, 2025	H135753
H2528294	Certificate of Analysis	Sep 09, 2025	H135753
H2528310	Certificate of Analysis	Sep 09, 2025	H135753
E2421156	Certificate of Analysis	May 25, 2024	H135753
E2421157	Certificate of Analysis	May 25, 2024	H135753
A2424140	Certificate of Analysis	Jan 27, 2024	H135753
A2424138	Certificate of Analysis	Jan 27, 2024	H135753
A2424133	Certificate of Analysis	Jan 27, 2024	H135753
A2424129	Certificate of Analysis	Jan 27, 2024	H135753
A2424125	Certificate of Analysis	Jan 27, 2024	H135753

Solubility	Soluble in water (>50 mg/ml).
Sensitivity	Hygroscopic；Light sensitive
Melt Point(°C)	232-233 °C
Molecular Weight	205.640 g/mol
XLogP3
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	205.051 Da
Monoisotopic Mass	205.051 Da
Topological Polar Surface Area	86.700 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	142.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

6-HydroxyDopamineHydrochloride - Moligand™, ≥97% , CAS No.28094-15-7

Why this grade

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

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