10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
(8R,9S)-Talazoparib ((8R,9S)-BMN-673) is an enantiomer of Talazoparib. (8R,9S)-Talazoparib is an PARP1 inhibitor, with an IC 50 of 144 nM
In Vitro
(8R,9S)-Talazoparib shows an EC 50 of 864 nM in cellular PARylation assay. (8R,9S)-Talazoparib shows an EC 50 of 1135 nM for Capan-1 cells (BRCA2 mutant). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:PARP-1 144 nM (IC 50 )
| Isomeric SMILES | CN1C(=NC=N1)[C@H]2[C@@H](NC3=CC(=CC4=C3C2=NNC4=O)F)C5=CC=C(C=C5)F |
|---|---|
| Alternate CAS | 1207456-00-5 |
| Molecular Weight | 380.35 |
| Reaxy-Rn | 19918515 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19918515&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
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