A 410099.1 - ≥98%(HPLC) , CAS No.762274-58-8

CAS: 762274-58-8 Cat. No.: A287066 Formula: C₂₇H₄₀N₄O₃·HCl Molecular Weight: 505.09 PubChem CID: 131858992

GRADE & PURITY ≥98%(HPLC)

Synonyms

N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

High affinity XIAP antagonist (Kd= 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell linesin vitro(EC50= 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%(HPLC)

Names and Identifiers

Canonical Smiles

CN[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H]2CCCC3=CC=CC=C23)=O)=O)C4CCCCC4)=O)C.Cl

InChIKey

OPCYOBWCDDJCFT-VOSOYEAFSA-N

PubChem CID

131858992

Molecular Weight

505.09

Chemical and Physical Properties

• Solubility: Solvent:water, Max Conc. mg/mL: 50.51, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 50.51, Max Conc. mM: 100

Frequently Asked Questions

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 762274-58-8, the molecular formula is C27H40N4O3·HCl, and the molecular weight is 505.09 g/mol. InChIKey OPCYOBWCDDJCFT-VOSOYEAFSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.