Ac-rC phosphoramidite monomer - ≥98%(Mixture of Diastereomers) , CAS No.121058-88-6

CAS: 121058-88-6 Cat. No.: B299807 Molecular Weight: 902.1 PubChem CID: 70700204

GRADE & PURITY ≥98%(Mixture of Diastereomers)

Synonyms

DMT-2'O-TBDMS-rC(ac) Phosphoramidite | N-[1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide | (2S,3S,4S,5S)-5-(4

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Overview

Product Application
Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).

Specifications

Synonyms

DMT-2'O-TBDMS-rC(ac) Phosphoramidite | N-[1-[(2S, 3S, 4S, 5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide | (2S, 3S, 4S, 5S)-5-(4

Specifications & Purity

≥98%(Mixture of Diastereomers)

Storage

Protected from light, Store at -20°C, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%(Mixture of Diastereomers)

Names and Identifiers

• Canonical Smiles: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
• IUPAC Name: N-[1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
• InChIKey: QKWKXYVKGFKODW-ZYRNLWDWSA-N
• INCHI: 1S/C47H64N5O9PSi/c1-32(2)52(33(3)4)62(58-30-16-28-48)60-42-40(59-44(43(42)61-63(11,12)46(6,7)8)51-29-27-41(49-34(5)53)50-45(51)54)31-57-47(35-17-14-13-15-18-35,36-19-23-38(55-9)24-20-36)37-21-25-39(56-10)26-22-37/h13-15,17-27,29,32-33,40,42-44H,16,30-31H2,1-12H3,(H,49,50,53,54)/t40-,42-,43-,44-,62?/m0/s1
• Isomeric SMILES: CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H](O[C@@H]([C@H]1O[Si](C)(C)C(C)(C)C)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
• PubChem CID: 70700204
• Molecular Weight: 902.1

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Triphenyl compounds

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Triphenyl compounds
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Triphenyl compounds
• Alternative Parents: Ribonucleoside phosphoramidites Glycosylamines Benzylethers N-acetylarylamines Anisoles Phenoxy compounds Methoxybenzenes Alkyl aryl ethers Pyrimidones Hydropyrimidines Imidolactams Monosaccharides Acetamides Trialkylheterosilanes Oxolanes Heteroaromatic compounds Silyl ethers Secondary carboxylic acid amides Azacyclic compounds Dialkyl ethers Oxacyclic compounds Organic metalloid salts Nitriles Hydrocarbon derivatives Carbonyl compounds Organic oxides
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Triphenyl compound - Ribonucleoside phosphoramidite - N-glycosyl compound - Glycosyl compound - Benzylether - N-acetylarylamine - Anisole - Phenoxy compound - Phenol ether - Methoxybenzene - N-arylamide - Alkyl aryl ether - Pyrimidone - Imidolactam - Hydropyrimidine - Monosaccharide - Pyrimidine - Monocyclic benzene moiety - Trialkylheterosilane - Heteroaromatic compound - Oxolane - Acetamide - Secondary carboxylic acid amide - Silyl ether - Carboxamide group - Organic metalloid salt - Azacycle - Oxacycle - Organoheterocyclic compound - Carboxylic acid derivative - Nitrile - Carbonitrile - Dialkyl ether - Ether - Organoheterosilane - Cyanide - Organic oxide - Hydrocarbon derivative - Organic oxygen compound - Organic metalloid moeity - Organonitrogen compound - Carbonyl group - Organic nitrogen compound - Organosilicon compound - Organooxygen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as triphenyl compounds. These are aromatic compounds containing a triphenyl moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Solubility：DMSO: 95 mg/mL (105.31 mM), sonification is recommended.
• Sensitivity: Moisture sensitive;Light sensitive
• Molecular Weight: 902.100 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 21
• Exact Mass: 901.421 Da
• Monoisotopic Mass: 901.421 Da
• Topological Polar Surface Area: 153.000 Ų
• Heavy Atom Count: 63
• Formal Charge: 0
• Complexity: 1560.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

XLogP3