ACET - ≥98%(HPLC) , CAS No.936095-50-0

CAS: 936095-50-0 Cat. No.: A287284 Molecular Weight: 429.45 PubChem CID: 118797384

GRADE & PURITY ≥98%(HPLC)

Synonyms

(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione

Storage

Room temperature

Shipped In

Normal

Specifications

Synonyms

(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2, 4-dione

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

Potent and selective GluK1 (formerly GluR5) containing kainate receptor antagonist (IC50= 7 nM) that displays selectivity over GluK2 (formerly GluR6) containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA receptor-i

Storage

Room temperature

Shipped In

Normal

Action Type

ANTAGONIST

Purity

≥98%(HPLC)

Names and Identifiers

• Canonical Smiles: CC1CN(C(=O)N(C1=O)CC2=C(SC(=C2)C3=CC=CC=C3)C(=O)O)CC(C(=O)O)N
• IUPAC Name: 3-[[3-(2-amino-2-carboxyethyl)-5-methyl-2,6-dioxo-1,3-diazinan-1-yl]methyl]-5-phenylthiophene-2-carboxylic acid
• InChIKey: OAAMYRWMIRGBQF-UHFFFAOYSA-N
• INCHI: 1S/C20H21N3O6S/c1-11-8-22(10-14(21)18(25)26)20(29)23(17(11)24)9-13-7-15(30-16(13)19(27)28)12-5-3-2-4-6-12/h2-7,11,14H,8-10,21H2,1H3,(H,25,26)(H,27,28)
• PubChem CID: 118797384
• Molecular Weight: 429.45

Chemical and Physical Properties

• Solubility: Solvent:3eq. NaOH, Max Conc. mg/mL: 8.59, Max Conc. mM: 20

References

1. Huizi Li, Tingyao Du, Qin Wang, Jianyu Guo, Siyong Zhang, Yan Lu.  (2023)  A new synthesis of O/N-doped porous carbon material for supercapacitors.  Journal of Energy Storage,      [PMID:] [10.1016/j.est.2023.107397]

2. Wang Mi, Shen Yanting, Hu Xiaoxiao, Zhu Yanyan, Wang Jing.  (2022)  Colorimetric/SERS dual-channel nanoprobe for reactive oxygen species monitoring in elucidating the mechanism of chemotherapeutic drugs action on cancer cells.  MICROCHIMICA ACTA,  189  (9): (1-11).  [PMID:36008738] [10.1007/s00604-022-05451-x]

3. Ye Tian, Qi Wang, Zhijian Peng, Shundong Guan, Xiuli Fu.  (2021)  Ni Foam-Supported Tin Oxide Nanowall Array: An Integrated Supercapacitor Anode.  MOLECULES,  26  (15): (4517).  [PMID:34361672] [10.3390/molecules26154517]