≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at 2-8°C,Protected from light,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
ADRA1D receptor antagonist 1 is a potent, selective and orally active α 1D adrenoceptor antagonist, with a K i of 1.6 nM
In Vitro
ADRA1D receptor antagonist 1 shows low hERG inhibition. ADRA1D receptor antagonist 1 exhibits higher selectivity for α1D-AR over α1A- and α1B-ARs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
ADRA1D receptor antagonist 1 (4.4 µg/kg; i.v.) dose-dependently decreases the non-voiding bladder contractions during the urinary storage phase in rats with BOO . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Rat with bladder outlet obstruction (BOO) Dosage: 4.4 µg/kg Administration: Intravenous injection Result: Dose-dependently decreased the non-voiding bladder contractions during urinary storage phase in rats with BOO.
Form:Solid
IC50& Target:Ki: 1.6 nM (α 1D adrenoceptor)
Specifications
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
ADRA1D receptor antagonist 1 is a potent, selective and orally active α 1D adrenoceptor antagonist, with a K i of 1.6 nM.
Storage
Store at 2-8°C, Protected from light, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ANTAGONIST
Purity
≥98%
Names and Identifiers
Molecular Weight
337.20
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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