Albumin solution human, CAS No.70024-90-7

CAS: 70024-90-7 Cat. No.: A754961 Molecular Weight: 66.5kD EC Number: 274-272-6

GRADE & PURITY 10% in 0.85% sodium chloride and 0.05% sodium azide, aseptically filled

Overview

Human serum albumin (HSA) is a monomeric, globular, and α-helical protein that constitutes a major part of human blood plasma proteins. This single-chain polypeptide protein contains 585 amino acid residues and 17 internal disulfide bridges and one free cysteine.

Human serum albumin undergoes three different post-translational modifications: oxidation, glycation, and S-nitrosylation. Modifications usually occur on the surface of the globular protein, and do not significantly affect conformation. However, modification strongly affects binding of fatty acids and drug molecules.

Application:

Albumin solution human has been used as a supplement in RPMI 1640 media during polymorphonuclear cell (PMN) incubation. It has also been used as a culture media for the differentiation and maturation of monocyte-derived dendritic cells.

Specifications

Product Name

Albumin solution human, CAS No.70024-90-7

Specifications & Purity

10% in 0.85% sodium chloride and 0.05% sodium azide, aseptically filled

Biochemical and Physiological Mechanisms

Human serum albumin (HSA) plays a vital role in the regulation of the colloidal osmotic pressure of blood. It also aids in the maintenance of metal ion homeostasis, including the transport and storage of transition metals. The high binding capacity of HSA

CAS

70024-90-7

Molecule Type

Small molecule

Storage and Shipping

Concentration

10% in 0.85% sodium chloride and 0.05% sodium azide, aseptically filled

Storage

Store at 2-8°C

Shipped In

Wet ice