Artificial Gastric Fluid is a solution formulated to mimic the composition and pH value of natural gastric fluid, complying with the specifications of the United States Pharmacopeia. It is mainly composed of sodium chloride, dilute acid, pepsin, etc., and undergoes sterile processing. This reagent is applicable for the testing of capsules, enteric-coated tablets, dropping pills and other preparations, and is particularly suitable for the testing of soft capsules and dropping pills with gelatin as the matrix. It is for research use only and not intended for clinical diagnosis or any other applications.
Operating Procedures (For Reference Only)
1. For the testing of capsules, enteric-coated tablets, dropping pills and other preparations, a lifting disintegration tester is generally used, which is mainly composed of a metal support and a basket equipped with baffles.
2. Immerse 6 units of the test capsules, enteric-coated tablets or dropping pills in the Simulated Gastric Fluid. They should disintegrate completely within 1 hour. If 1 unit fails to disintegrate completely, another 6 units shall be taken for retesting, and all of them shall meet the requirements.
3. For other experiments, operations shall be performed in accordance with the specific experimental requirements.
Precautions
1. Artificial Gastric Fluid (USP, Sterile) is a sterile solution. If sterility is required for the experiment, aseptic techniques shall be strictly followed during operation.
2. Avoid repeated freezing and thawing of Artificial Gastric Fluid (USP, Sterile) to prevent the decrease of its effectiveness.
3. Please use the reagent as soon as possible after opening to avoid affecting the results of subsequent experiments.
4. For your safety and health, please wear a lab coat and disposable gloves during operation.
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