10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Aspartame (SC-18862) is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages.
In vitro
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥99%
| ALogP | -2.7 |
|---|
| Isomeric SMILES | COC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(=O)O)N |
|---|---|
| WGK Germany | 2 |
| RTECS | WM3407000 |
| Molecular Weight | 294.3 |
| Beilstein | 2223850 |
| Reaxy-Rn | 4707041 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4707041&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Specific Rotation[α] | 14.5 ° (C=4, 15mol/L Formic Acid) |
|---|---|
| Melt Point(°C) | 248-250°C |
| 1. Zhijian Ke, Junyun Song, Jingrui Ma, Mengting Wang, Haiguang Mao, Chunli Xia, Lili Qi, Yidong Zhou, Jinbo Wang. (2023) Isolation and characterization of the aspartame-degrading strain Pseudarthrobacter sp. AS-1. ENVIRONMENTAL POLLUTION, [PMID:37944888] [10.1016/j.envpol.2023.122883] |
| 2. Jun Dong, Haoran Wu, Yi Cao, Jiaxin Yuan, Qingyan Han, Wei Gao, Chengyun Zhang, Jianxia Qi, Mengtao Sun. (2022) Capillary-force-assisted self-assembly of gold nanoparticles into highly ordered plasmonic thin films for ultrasensitive SERS. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 25 (3): (1649-1658). [PMID:36541051] [10.1039/D2CP05158C] |
| 3. Qichao Ye, Chen Men, Lili Tian, Yuxin Liu, Lei Zhan, Yuan Fang Li, Cheng Zhi Huang, Shu Jun Zhen. (2021) Preparation of a molecularly imprinted test strip for point-of-care detection of thiodiglycol, a sulfur mustard poisoning metabolic marker. TALANTA, [PMID:34364498] [10.1016/j.talanta.2021.122701] |
| 4. Ferry Saputra, Yu-Heng Lai, Rey Arturo T. Fernandez, Allan Patrick G. Macabeo, Hong-Thih Lai, Jong-Chin Huang, Chung-Der Hsiao. (2021) Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae. Biology-Basel, 10 (6): (548). [PMID:34207293] [10.3390/biology10060548] |
| 5. Sun Xiao-Dong, Wu Hai-Long, Liu Zhi, Chen Yue, Liu Qian, Ding Yu-Jie, Yu Ru-Qin. (2018) Rapid and Sensitive Detection of Multi-Class Food Additives in Beverages for Quality Control by Using HPLC-DAD and Chemometrics Methods. Food Analytical Methods, 12 (2): (381-393). [PMID:] [10.1007/s12161-018-1370-3] |
| 6. Hongmei Zhang, Shixin Sun, Yanqing Wang, Zhenghao Fei, Jian Cao. (2018) Binding mechanism of five typical sweeteners with bovine serum albumin. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:30015031] [10.1016/j.saa.2018.07.013] |
| 7. Li’na Qiao, Sihua Qian, Yuhui Wang, Hengwei Lin. (2018) A colorimetric sensor array based on sulfuric acid assisted KMnO4 fading for the detection and identification of pesticides. TALANTA, [PMID:29426516] [10.1016/j.talanta.2018.01.029] |
| 8. Hongkun Zhao, Chunning Chen, Yalei Wang, Jiaqi Liu, Jiaxin Lu, Jingtong Zhai, Rui Li, Nan Lu. (2025) A paper-based SERS/colorimetry substrate for reliable detection. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:39824014] [10.1016/j.saa.2025.125731] |
| 9. Bin Qiu, Zhao Chen, Xiaomei Pei, Zhenggang Cui, Binglei Song. (2025) Viscoelastic behavior of wormlike micellar solutions formed by an aspartame-based bicephalous anionic surfactant. Soft Matter, 21 (8): (1583-1591). [PMID:39902528] [10.1039/D5SM00013K] |
| 10. Linyang Song, Xiaoyi He, Mengxia Wang, Lixia Li, Jing Liu, Guoying Li, Junhua Yang. (2023) IFN-γ mediated neuroinflammation and behaviour abnormality after maternal exposure to low dose mixture of food additives and pesticides. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:] [10.1080/09540105.2023.2226841] |
| 11. Weiwei Jiang, Yuwei Cheng, Lei Hou, Ying Huang, Sizhen Wang, Yunchang Zhang, Tao Jiang, Feng Yang, Zhiqiang Ma. (2024) A dual-prodrug nanogel combining Vorinostat and Pyropheophorbide a for a high efficient photochemotherapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:38977163] [10.1016/j.ijpharm.2024.124422] |
| 12. Yan Bai, Ji Feng, Xiao-Yu Wu, Zhi-Sheng Yao, Yue-Tong Liu, Yu-Hong Li, Guo-Dong Lu, Kun Xue. (2026) Aspartame exacerbates cerebral ischemia–reperfusion injury via mitochondrial dysfunction and ERK/CREB1 pathway suppression. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, [PMID:41762991] [10.1016/j.ecoenv.2026.119938] |
| 13. Shiqin Gong, Ziqi Li, Fang Liu, Yi Xiao. (2026) Aspartame induces autophagy to extend healthspan in Caenorhabditis elegans via mTORC1/LET-363-TFEB/HLH-30 pathway. Food Bioscience, [PMID:] [10.1016/j.fbio.2026.108775] |
