β-Cembrenediol - ≥98% , CAS No.57605-81-9

CAS: 57605-81-9 Cat. No.: C275839 Molecular Weight: 306.48

GRADE & PURITY ≥98%

Synonyms

(1R,3R,4Z,8Z,12S,13Z)-1,5,9-trimethyl-12-propan-2-ylcyclotetradeca-4,8,13-triene-1,3-diol | beta -Cembrenediol | (1R-(1R*,3R*,4E,8E,12S*,13E))-1,5,9-Trimethyl-12-(1-methylethyl)-4,8,13-cyclotetradecatriene-1,3-diol | CCRIS 5453 | beta-4,8,13-Duvatriene-1,

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Overview

b-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments.

Specifications

Synonyms

(1R, 3R, 4Z, 8Z, 12S, 13Z)-1, 5, 9-trimethyl-12-propan-2-ylcyclotetradeca-4, 8, 13-triene-1, 3-diol | beta -Cembrenediol | (1R-(1R*, 3R*, 4E, 8E, 12S*, 13E))-1, 5, 9-Trimethyl-12-(1-methylethyl)-4, 8, 13-cyclotetradecatriene-1, 3-diol | CCRIS 5453 | beta-4, 8, 13-Duvatriene-1,

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Tumor promotion inhibitor. Inhibits the early antigen of the Epstein-Bar virus.

Source

Synthetic

Storage

Protected from light, Store at -20°C, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CC1=CCCC(=CC(CC(C=CC(CC1)C(C)C)(C)O)O)C
• IUPAC Name: (1R,3R,4Z,8Z,12S,13Z)-1,5,9-trimethyl-12-propan-2-ylcyclotetradeca-4,8,13-triene-1,3-diol
• InChIKey: RIVKDDXPCFBMOV-PCFHHCMKSA-N
• INCHI: 1S/C20H34O2/c1-15(2)18-10-9-16(3)7-6-8-17(4)13-19(21)14-20(5,22)12-11-18/h7,11-13,15,18-19,21-22H,6,8-10,14H2,1-5H3/b12-11-,16-7-,17-13-/t18-,19+,20+/m1/s1
• Isomeric SMILES: C/C/1=C/CC/C(=C\[C@@H](C[C@@](/C=C\[C@@H](CC1)C(C)C)(C)O)O)/C
• Molecular Weight: 306.48
• Reaxy-Rn: 24583056
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24583056&ln=

Chemical and Physical Properties

• Solubility: Chloroform (Slightly), Methanol (Slightly);DMF: 30 mg/ml；DMSO: 30 mg/ml；Ethanol: 30 mg/ml；Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
• Sensitivity: Light sensitive
• Melt Point(°C): 106-112°C

References

1. Xiaowei Zhang, Tianyu Dong, Dan Chen, Haowei Sun, Anchuan Xu, Chunqiong Wang, Dan Li, Jieyun Cai, Lingduo Bu, Ke Zhang, Haitao Chen.  (2025)  Unraveling flavor formation mechanism of cigar smoke through volatile compounds in cigar smoke and potential precursors in cigar tobacco.  Frontiers in Plant Science,      [PMID:41079311] [10.3389/fpls.2025.1672119]