β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate(NADP) - ≥97% , CAS No.1184-16-3

CAS: 1184-16-3 Cat. No.: N107170 Molecular Weight: 765.39(anhydrous) Beilstein Registry Number: 4779954 EC Number: 214-664-6 PubChem CID: 2724369

GRADE & PURITY ≥97%

Synonyms

NADP sodium salt | AC3111 | MFCD00036973 | NR2O7P57YA | beta-Nicotinamide adenine dinudeotide phosphate sodium salt (NADP) | NADP Sodium | coenzyme II | AC-37027 | NSC-20273 | AS-15969 | AKOS025310891 | Sodium (2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(((

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Specifications

Synonyms

NADP sodium salt | AC3111 | MFCD00036973 | NR2O7P57YA | beta-Nicotinamide adenine dinudeotide phosphate sodium salt (NADP) | NADP Sodium | coenzyme II | AC-37027 | NSC-20273 | AS-15969 | AKOS025310891 | Sodium (2R, 3R, 4R, 5R)-2-(6-amino-9H-purin-9-yl)-5-(((

Specifications & Purity

≥97%

Biochemical and Physiological Mechanisms

Electron acceptor

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%

Names and Identifiers

• Canonical Smiles: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O)C(=O)N.[Na+]
• IUPAC Name: sodium;[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
• InChIKey: JNUMDLCHLVUHFS-QYZPTAICSA-M
• INCHI: 1S/C21H28N7O17P3.Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);/q;+1/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;/m1./s1
• Isomeric SMILES: C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O)C(=O)N.[Na+]
• WGK Germany: 3
• Alternate CAS: 698999-85-8
• PubChem CID: 2724369
• Molecular Weight: 765.39(anhydrous)
• Beilstein: 4779954

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class (5'->5')-dinucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: (5'->5')-dinucleotides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: (5'->5')-dinucleotides
• Alternative Parents: Purine nucleotide sugars Purine ribonucleoside diphosphates Purine ribonucleoside 2',5'-bisphosphates Nicotinamide nucleotides Pentose phosphates Glycosylamines 6-aminopurines Monosaccharide phosphates Organic pyrophosphates Nicotinamides Aminopyrimidines and derivatives Monoalkyl phosphates Imidolactams Pyridinium derivatives N-substituted imidazoles Tetrahydrofurans Vinylogous amides Heteroaromatic compounds Primary carboxylic acid amides Amino acids and derivatives Secondary alcohols Oxacyclic compounds Azacyclic compounds Organic oxides Primary amines Hydrocarbon derivatives Organopnictogen compounds Organic sodium salts Organic zwitterions
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: (5'->5')-dinucleotide - Purine nucleotide sugar - Purine ribonucleoside diphosphate - Purine ribonucleoside bisphosphate - Purine ribonucleoside 2',5'-bisphosphate - Nicotinamide-nucleotide - Pyridine nucleotide - Pentose-5-phosphate - Pentose phosphate - N-glycosyl compound - Glycosyl compound - 6-aminopurine - Monosaccharide phosphate - Organic pyrophosphate - Pyridine carboxylic acid or derivatives - Imidazopyrimidine - Purine - Nicotinamide - Monoalkyl phosphate - Aminopyrimidine - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Imidolactam - Alkyl phosphate - Pyridine - Pyridinium - Pyrimidine - Vinylogous amide - Azole - Tetrahydrofuran - Imidazole - Heteroaromatic compound - Primary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Secondary alcohol - Carboxylic acid derivative - Organoheterocyclic compound - Organic alkali metal salt - Azacycle - Oxacycle - Primary amine - Organic nitrogen compound - Hydrocarbon derivative - Alcohol - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic salt - Organic zwitterion - Amine - Organonitrogen compound - Organooxygen compound - Organic sodium salt - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water.
• Sensitivity: heat sensitive
• Melt Point(°C): 178 °C(dec.)
• Molecular Weight: 765.400 g/mol
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 21
• Rotatable Bond Count: 13
• Exact Mass: 765.057 Da
• Monoisotopic Mass: 765.057 Da
• Topological Polar Surface Area: 370.000 Ų
• Heavy Atom Count: 49
• Formal Charge: 0
• Complexity: 1290.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Yang Guang-xi, Peng De-liang, Chen Lin, Qian Yu, He Le, Chen Xiao-yan, Hong Wen-bin, Wu Cai-ming, Chen Hang-zi.  (2025)  Activation of AKT via a dual mechanism enhances the susceptibility of melanoma cells to glucose deprivation.  Cell Death & Disease,  16  (1): (1-15).  [PMID:40774947] [10.1038/s41419-025-07906-4]

2. Liya Zhou, Hengrui Zuo, Yunting Liu, Chunliu Li, Ying He, Guanhua Liu, Li Ma, Ruxue Feng, Yanjun Jiang.  (2026)  Mining and Modification of Imine Reductase for Asymmetric Reduction of Cyclic Imines.  ChemCatChem,  18  (1): (e01574).  [PMID:] [10.1002/cctc.202501574]