Bis(maltolato)oxovanadium(IV) - 10mM in DMSO , CAS No.38213-69-3

CAS: 38213-69-3 Cat. No.: B423769 Molecular Weight: 317.15 EC Number: 690-708-1

GRADE & PURITY 10mM in DMSO

Synonyms

bis(maltolato)oxovanadium(IV)|38213-69-3|HA933D78YW|2-methyl-4-oxopyran-3-olate;oxovanadium(2+)|Bmov(IV)|Vanadium, bis(3-hydroxy-2-methyl-4H-pyran-4-onato-O3,O4)oxo-, (SP-5-31)-|BIS((2-METHYL-4-OXO-PYRAN-3-YL)OXY)-OXO-VANADIUM|UNII-HA933D78YW|VO(MA)2|2-me

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Bis(maltolato)oxovanadium(IV) is a potent insulin mimic. Results have shown that BMOV significantly decreases plasma glucose levels in diabetic rats at all given doses, and restores hyperglycemic values to normal. Bis(maltolato)oxovanadium(IV) inhibits protein tyrosine phosphatases.

Specifications

Synonyms

bis(maltolato)oxovanadium(IV) | 38213-69-3 | HA933D78YW | 2-methyl-4-oxopyran-3-olate;oxovanadium(2+) | Bmov(IV) | Vanadium, bis(3-hydroxy-2-methyl-4H-pyran-4-onato-O3, O4)oxo-, (SP-5-31)- | BIS((2-METHYL-4-OXO-PYRAN-3-YL)OXY)-OXO-VANADIUM | UNII-HA933D78YW | VO(MA)2 | 2-me

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

BMOV is a potent, orally available vanadium complex that acts as insulin mimetic. Apparently, BMOV anti-diabetic effect results from enhancement of the tyrosine-phosphorylation of insulin receptor by inhibition of the protein tyrosine phosphatase-1B (PTP-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: CC1=C(C(=O)C=CO1)[O-].CC1=C(C(=O)C=CO1)[O-].O=[V+2]
• IUPAC Name: 2-methyl-4-oxopyran-3-olate;oxovanadium(2+)
• InChIKey: XUOLEICXAPEOSI-UHFFFAOYSA-L
• INCHI: 1S/2C6H6O3.O.V/c2*1-4-6(8)5(7)2-3-9-4;;/h2*2-3,8H,1H3;;/q;;;+2/p-2
• Isomeric SMILES: CC1=C(C(=O)C=CO1)[O-].CC1=C(C(=O)C=CO1)[O-].O=[V+2]
• WGK Germany: 3
• Molecular Weight: 317.15
• Reaxy-Rn: 15489298
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=15489298&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Pyrans
      • Subclass Pyranones and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Pyrans
• Subclass: Pyranones and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyranones and derivatives
• Alternative Parents: Heteroaromatic compounds Cyclic ketones Oxacyclic compounds Organic transition metal salts Organic zwitterions Organic oxides Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: Pyranone - Heteroaromatic compound - Cyclic ketone - Oxacycle - Organic transition metal salt - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organic salt - Organic zwitterion - Organooxygen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as pyranones and derivatives. These are compounds containing a pyran ring which bears a ketone.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Melt Point(°C): >300°C (lit.)(dec.)
• Molecular Weight: 317.140 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 0
• Exact Mass: 316.987 Da
• Monoisotopic Mass: 316.987 Da
• Topological Polar Surface Area: 116.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 202.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

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