EGFR
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852 products
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- GW 583340 dihydrochlorideMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%(HPLC)◐ .Made to order · 8–12 wks Item #: G286712View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[2-[(2-methylsulfonylethylamino)methyl]-1,3-thiazol-4-yl]quinazolin-4-amine;dihydrochloride
- SMILES
- CS(=O)(=O)CCNCC1=NC(=CS1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.Cl.Cl
- InChIKey
- WIMITXDBYLKRKB-UHFFFAOYSA-N
- InChI
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- Synonyms
- N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[2-[[[2-(methylsulfonyl)ethyl]amino]methyl]-4-thiazolyl]-4-quinazoli...
- AEE788 (NVP-AEE788), Vascular endothelial growth factor receptor 1 inhibitorCAS: 497839-62-0 Formula: C27H32N6 Molecular Weight: 440.58● In Stock — US Item #: A126830View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- SMILES
- CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4NC(C)C5=CC=CC=C5
- InChIKey
- OONFNUWBHFSNBT-HXUWFJFHSA-N
- InChI
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- Synonyms
- 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[3,2-e]pyrimidin-4-amine | 7,9-Dimethyl-...
- ZM306416 hydrochloride● In Stock — US Item #: Z276165View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC.Cl
- InChIKey
- SCUXIROMWPQVJO-UHFFFAOYSA-N
- InChI
- 1S/C16H13ClFN3O2.ClH/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18;/h3-8H,1-2H3,(H,19,20,21);1H
- Synonyms
- 4-[(4'-Chloro-2'-fluoro)phenylamino]-6,7-dimethoxyquinazolinehydrochloride
- ZM 449829Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US Item #: Z275707View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-naphthalen-2-ylprop-2-en-1-one
- SMILES
- C=CC(=O)C1=CC2=CC=CC=C2C=C1
- InChIKey
- FOTCGZPFSUWZBN-UHFFFAOYSA-N
- InChI
- 1S/C13H10O/c1-2-13(14)12-8-7-10-5-3-4-6-11(10)9-12/h2-9H,1H2
- Synonyms
- 1-(2-Naphthalenyl)-2-propen-1-one
- Lapatinib, Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US Item #: L126696View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
- SMILES
- CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
- InChIKey
- BCFGMOOMADDAQU-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- EN300-117254 | Kinome_3685 | 231277-92-2 (free base) | D08108 | GSK 572016 | GTPL5692 | Lapatinib free base | N-(3-ch...
- GW2974CAS: 202272-68-2 Formula: C23H21N7 Molecular Weight: 395.46Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US Item #: G337820View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-N-(1-benzylindazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine
- SMILES
- CN(C)C1=NC=C2C(=C1)C(=NC=N2)NC3=CC4=C(C=C3)N(N=C4)CC5=CC=CC=C5
- InChIKey
- DYYZXRCFCVDSKD-UHFFFAOYSA-N
- InChI
- 1S/C23H21N7/c1-29(2)22-11-19-20(13-24-22)25-15-26-23(19)28-18-8-9-21-17(10-18)12-27-30(21)14-16-6-4-3-5-7-16/h3-13,15H,14H2,1-2H3,(H,25,26,28)
- Synonyms
- EGFR/HER2 Inhibitor | EU-0100509 | HMS3303J07 | SCHEMBL1737530 | J-013131 | NSC756204 | NSC-756204 | Q27167122 | DTXS...
- SJF 1521◐ .Made to order · 8–12 wks Item #: S288730View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)COCCOCCOCCOC4=CC=C(C=C4)C5=CC6=C(C=C5)N=CN=C6NC7=CC(=C(C=C7)OCC8=CC(=CC=C8)F)Cl)O
- InChIKey
- XZNORRXEBCTXPB-KHBXAZQSSA-N
- InChI
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- Synonyms
- (2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)phenoxy)-4-oxo-...
- SJF 1528◐ .Made to order · 8–12 wks Item #: S287968View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)COCCOCCOC4=CC=C(C=C4)C5=CC6=C(C=C5)N=CN=C6NC7=CC(=C(C=C7)OCC8=CC(=CC=C8)F)Cl)O
- InChIKey
- ZSCOIFSUFMYZEZ-YSWDPXALSA-N
- InChI
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- Synonyms
- (2S,4R)-1-((S)-2-(2-(2-(2-(4-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6- yl)phenoxy)ethoxy)ethoxy...
- SU-5402CAS: 215543-92-3 Formula: C17H16N2O3 Molecular Weight: 296.32● In Stock — US Item #: S276590View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
- SMILES
- CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O
- InChIKey
- JNDVEAXZWJIOKB-JYRVWZFOSA-N
- InChI
- 1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
- Synonyms
- HY-10407G | BCPP000060 | SCHEMBL177917 | SU 5402 | su5402 | SU-5402 | (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)meth...
- 1,8-Dihydroxy-3-methylanthraquinoneSolid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US Item #: D101143View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1,8-dihydroxy-3-methylanthracene-9,10-dione
- SMILES
- CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O
- InChIKey
- LQGUBLBATBMXHT-UHFFFAOYSA-N
- InChI
- 1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
- Synonyms
- Chrysophansaeure | NSC 646567 | BCP23439 | MFCD00001208 | Anthraquinone, 1,8-dihydroxy-3-methyl- | Spectrum_000792 | ...
- TX-1123◐ .Made to order · 8–12 wks Item #: T339226View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]cyclopent-4-ene-1,3-dione
- SMILES
- CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C2C(=O)C=CC2=O
- InChIKey
- VUEUMQIBGLKJJD-UHFFFAOYSA-N
- InChI
- 1S/C20H24O3/c1-19(2,3)14-10-12(9-13-16(21)7-8-17(13)22)11-15(18(14)23)20(4,5)6/h7-11,23H,1-6H3
- Synonyms
- 2-((3,5-di-tert-Butyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione
- AG-1478 (Tyrphostin AG-1478)● In Stock — US Item #: A126582View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC
- InChIKey
- GFNNBHLJANVSQV-UHFFFAOYSA-N
- InChI
- 1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
- Synonyms
- AG 1478 | HY-13524 | Tyrphostin AG-1478;NSC 693255 | Bio1_001322 | EX-A1236 | Maybridge1_004001 | HMS3229O03 | Tox21_...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.