GPCR Pathway

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  1. Chlorpromazine-d₆ Hydrochloride
    CAS: 1228182-46-4 EC Number: 688-173-4 Formula: C17D6H13ClN2S·HCl Molecular Weight: 361.36
    Out of Stock Item #: C134798
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    IUPAC Name
    3-(2-chlorophenothiazin-10-yl)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride
    SMILES
    CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl
    InChIKey
    FBSMERQALIEGJT-TXHXQZCNSA-N
    InChI
    1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H/i1D3,2D3;
    Synonyms
    DTXSID60746836 | Chlorpromazine D6 Hydrochloride | Klorproman-d6 | A890948 | Chlorpromazin HCl-d6 | 1228182-46-4 | HY...
  2. 5'-Adenylic Acid(5'-AMP), Gating inhibitor of TRPM4
    CAS: 61-19-8 EC Number: 200-500-0 Formula: C10H14N5O7P Molecular Weight: 347.22
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: A136967
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    IUPAC Name
    [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
    SMILES
    C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O)N
    InChIKey
    UDMBCSSLTHHNCD-KQYNXXCUSA-N
    InChI
    1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/show more
    Synonyms
    5'-adenylic acid | Adenosine monophosphate | Muscle adenylate | 8gpb | Monophosphadenine | SCHEMBL5588 | adenosine 5'...
  3. Arecoline, Agonist of M 1 receptor;Agonist of M 2 receptor;Agonist of M 3 receptor;Agonist of M 4 receptor;Agonist of M 5 receptor
    CAS: 63-75-2 EC Number: 200-565-5 Formula: C8H13NO2 Molecular Weight: 155.19
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A348021
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    IUPAC Name
    methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate
    SMILES
    CN1CCC=C(C1)C(=O)OC
    InChIKey
    HJJPJSXJAXAIPN-UHFFFAOYSA-N
    InChI
    1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3
    Synonyms
    Lopac0_000049 | Methyl N-methyltetrahydronicotinate | Q423515 | Spectrum_000055 | BSPBio_000324 | L000795 | 63-75-2 (...
  4. Benperidol(Anquil), Dopamine D2 receptor antagonist
    CAS: 2062-84-2 EC Number: 218-172-2 Formula: C22H24FN3O2 Molecular Weight: 381.44
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    Out of Stock Item #: B607988
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    IUPAC Name
    3-[1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]-1H-benzimidazol-2-one
    SMILES
    C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(=O)C4=CC=C(C=C4)F
    InChIKey
    FEBOTPHFXYHVPL-UHFFFAOYSA-N
    InChI
    1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28)
    Synonyms
    3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one | 97O6X78C53 | BENPERIDOL [WHO-DD] | CAS_20...
  5. JTC-801 free base, Antagonist of NOP receptor
    CAS: 244218-93-7 Formula: C26H25N3O2 Molecular Weight: 411.50
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: J611284
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    IUPAC Name
    N-(4-amino-2-methylquinolin-6-yl)-2-[(4-ethylphenoxy)methyl]benzamide
    SMILES
    CCc1ccc(cc1)OCc1ccccc1C(=O)Nc1ccc2c(c1)c(N)cc(n2)C
    InChIKey
    VTGBZWHPJFMTKS-UHFFFAOYSA-N
    InChI
    1S/C26H25N3O2/c1-3-18-8-11-21(12-9-18)31-16-19-6-4-5-7-22(19)26(30)29-20-10-13-25-23(15-20)24(27)14-17(2)28-25/h4-15H,3,16H2,1-2H3,(H2,27,28)(H,29,30)
    Synonyms
    BRD-K17705806-003-01-0 | SCHEMBL4916443 | BXU45ZH6LI | Q6109058 | GTPL1692 | NCGC00161418-02 | CHEBI:92314 | Benzamid...
  6. Imiloxan(RS-21361), Antagonist of α 2B-adrenoceptor
    CAS: 81167-16-0 Formula: C14H16N2O2 Molecular Weight: 244.29
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: I611041
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    IUPAC Name
    2-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-1-ethylimidazole
    SMILES
    CCn1ccnc1CC1COc2c(O1)cccc2
    InChIKey
    UXABARREKCJULM-UHFFFAOYSA-N
    InChI
    1S/C14H16N2O2/c1-2-16-8-7-15-14(16)9-11-10-17-12-5-3-4-6-13(12)18-11/h3-8,11H,2,9-10H2,1H3
    Synonyms
    NCGC00015570-04 | GNF-Pf-2156 | Tox21_110175_1 | Imiloxano [Spanish] | PDSP2_001483 | 1H-Imidazole, 2-[(2,3-dihydro-1...
  7. (-)-Vesamicol (AH5183)
    CAS: 112709-59-8 Formula: C17H25NO Molecular Weight: 259.39
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    Out of Stock Item #: V668367
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    IUPAC Name
    (1R,2R)-2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol
    SMILES
    C1CCC(C(C1)N2CCC(CC2)C3=CC=CC=C3)O
    InChIKey
    YSSBJODGIYRAMI-IAGOWNOFSA-N
    InChI
    1S/C17H25NO/c19-17-9-5-4-8-16(17)18-12-10-15(11-13-18)14-6-2-1-3-7-14/h1-3,6-7,15-17,19H,4-5,8-13H2/t16-,17-/m1/s1
    Synonyms
    vesamicol | (-)-Vesamicol | Vesamicol, (+/-)- | (1R,2R)-2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol | 3D416V0FLM | (1R,...
  8. Recombinant Human PTH1R/PTHR1 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)
    In Stock Item #: rp149790
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    Technical Identifiers
    Species
    Human
    Accession #
    Q03431
    Expression system
    HEK293
    Protein Day
    C-His
    Endotoxin Concentration
    <0.1 EU/μg
    Bioactivity
    When Recombinant Human PTH1R/PTHR1 is used at 2 μg/mL, the concentration of biotinylated human PTHrP that produces 50% of the optimal binding response is found to be approximately 0.03‑0.12 μg/mL.
    Synonyms
    Parathyroid hormone 1 receptor | PTH/PTHr receptor | PTH/PTHrP type I receptor | PTH1 receptor | Parathyroid Hormone ...
  9. Recombinant Human GLP-1R Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)
    Out of Stock Item #: rp146461
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    Technical Identifiers
    Species
    Human
    Accession #
    P43220
    Expression system
    HEK293
    Protein Day
    C-His
    Endotoxin Concentration
    <0.1 EU/μg
    Bioactivity
    Measured by its binding ability in a functional ELISA. When GLP-1 peptide is immobilized at 0.250 µg/mL (100 µL/well), Recombinant Human GLP-1R His-tag binds with an ED50 of 5.00-30.0 ng/mL.
    Synonyms
    GLP-1 receptor | GLP-1R | GLP-1-R | GLP1R | GLP-1R | GLP-1-R | glucagon-like peptide 1 receptor | MGC138331 | Glucago...
  10. Recombinant Human Frizzled-4 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. Fc tag ? Fc tag grade — recombinant protein bearing a Fc tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. The Fc tag aids dimerization and protein-A/G capture. ≥95%(SDS-PAGE)
    In Stock Item #: rp146167
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    Technical Identifiers
    Species
    Human
    Accession #
    Q9ULV1
    Expression system
    HEK293
    Protein Day
    C-hFc & His
    Endotoxin Concentration
    <0.1 EU/μg
    Bioactivity
    Measured by its binding ability in a functional ELISA. In a 100 µL reaction mixture containing biotinylated rmWnt-5a at 100 ng/mL and rhFrizzled-4/Fc Chimera dilutions at 0.1-2,000 ng/mL, the concentration of rhFrizzled-4/Fc Chimera that produces 50% of the optimal binding response is found to be approximately 15-60 ng/mL.
    Synonyms
    Fz-4 | FzE4 | hFz4 | CD344 | CD344 antigen | EVR1 | exudative vitreoretinopathy 1 | FEVR | frizzled (Drosophila) homo...
  11. Recombinant Human Legumain/Asparaginyl Endopeptidase Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)
    In Stock Item #: rp184063
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    Technical Identifiers
    Species
    Human
    Accession #
    Q99538
    Expression system
    HEK293
    Protein Day
    C-His
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    Testing in progress
    Synonyms
    AEP | Asparaginyl Endopeptidase | cysteine protease 1 | Legumain | LGMN | LGMN1 | Protease, cysteine 1 | protease, cy...
  12. Recombinant Human Frizzled-1 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. Fc tag ? Fc tag grade — recombinant protein bearing a Fc tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. The Fc tag aids dimerization and protein-A/G capture. ≥95%(SDS-PAGE)
    In Stock Item #: rp166452
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    Q9UP38
    Expression system
    HEK293
    Protein Day
    C-hFc & His
    Endotoxin Concentration
    <0.1 EU/μg
    Bioactivity
    Measured by its binding ability in a functional ELISA. In a 100 µL reaction mixture containing biotinylated rmWnt-5a at 100 ng/mL and rhFrizzled-1/Fc Chimera dilutions at 0.1-8,000 ng/mL, the concentration of rhFrizzled-1/Fc Chimera that produces 50% of the optimal binding response is found to be approximately 20-80 ng/mL. Optimal concentrations should be determined by each laboratory for each application.
    Synonyms
    DKFZp564G072 | FLJ95923 | frizzled family receptor 1 | frizzled homolog 1 | frizzled, Drosophila, homolog of, 1 | Fri...
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