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CGS 19755 - Moligand™ , Antagonist of GluN2A;Antagonist of GluN2B;Antagonist of GluN2C;Antagonist of GluN2D, CAS No.110347-85-8, Antagonist of GluN2A;Antagonist of GluN2B;Antagonist of GluN2C;Antagonist of GluN2D

CAS: 110347-85-8 Cat. No.: C287470 Molecular Weight: 223.17
COA
CGS 19755 - Moligand™ CAS No(110347-85-8) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
Synonyms
AKOS015914119 | 2-Piperidinecarboxylic acid, 4-(phosphonomethyl)-, (2R,4S)- | 4VGJ4A41L2 | CAS-110347-85-8 | N0905W44Y3 | SCHEMBL120234 | 4-Phosphonomethyl-piperidine-2-carboxylic acid | CGS19755 | CGS-19755 | 4-Phosphonomethyl-piperidine-2-carboxylic aci
Storage
Room temperature
Shipped In
Normal
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
C287470-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$335.90
50mg
C287470-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,411.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
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Why this grade

Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
AKOS015914119 | 2-Piperidinecarboxylic acid, 4-(phosphonomethyl)-, (2R, 4S)- | 4VGJ4A41L2 | CAS-110347-85-8 | N0905W44Y3 | SCHEMBL120234 | 4-Phosphonomethyl-piperidine-2-carboxylic acid | CGS19755 | CGS-19755 | 4-Phosphonomethyl-piperidine-2-carboxylic aci
Specifications & Purity
Moligand™
Biochemical and Physiological Mechanisms
Potent, competitive NMDA receptor antagonist. Anticonvulsant and neuroprotective.
Storage
Room temperature
Shipped In
Normal
Grade
Moligand™
Action Type
ANTAGONIST
Mechanism of action
Antagonist of GluN2A;Antagonist of GluN2B;Antagonist of GluN2C;Antagonist of GluN2D
Names and Identifiers
Canonical SmilesC1CNC(CC1CP(=O)(O)O)C(=O)O
IUPAC Name(2S,4R)-4-(phosphonomethyl)piperidine-2-carboxylic acid
InChIKeyLPMRCCNDNGONCD-RITPCOANSA-N
INCHI1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1
Isomeric SMILES C1CN[C@@H](C[C@@H]1CP(=O)(O)O)C(=O)O
Molecular Weight 223.17
Reaxy-Rn 4253562
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4253562&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
Direct ParentL-alpha-amino acids
Alternative Parents Piperidinecarboxylic acids  Organic phosphonic acids  Amino acids  Monocarboxylic acids and derivatives  Dialkylamines  Carboxylic acids  Azacyclic compounds  Organopnictogen compounds  Organophosphorus compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic heteromonocyclic compounds
Substituents L-alpha-amino acid - Piperidinecarboxylic acid - Piperidine - Organophosphonic acid - Organophosphonic acid derivative - Amino acid - Carboxylic acid - Secondary aliphatic amine - Monocarboxylic acid or derivatives - Secondary amine - Organoheterocyclic compound - Azacycle - Organophosphorus compound - Organooxygen compound - Organonitrogen compound - Organic oxide - Organopnictogen compound - Hydrocarbon derivative - Organic oxygen compound - Amine - Carbonyl group - Organic nitrogen compound - Aliphatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
External Descriptors non-proteinogenic alpha-amino acid
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
GRIN2A Tclin Glutamate receptor ionotropic, NMDA 2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2B Tclin Glutamate receptor ionotropic, NMDA 2B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2C Tclin Glutamate receptor ionotropic, NMDA 2C (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2D Tclin Glutamate receptor ionotropic, NMDA 2D (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2A Tclin Glutamate [NMDA] receptor subunit epsilon 1 (112 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIA1 Tclin Glutamate receptor ionotropic, AMPA 1 (277 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIK3 Tclin Glutamate receptor ionotropic kainate 3 (50 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Huh-7 (12904 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate [NMDA] receptor (933 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor (6467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolvent:water, Max Conc. mg/mL: 5.58, Max Conc. mM: 25
Molecular Weight223.160 g/mol
XLogP3-3.900
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass223.061 Da
Monoisotopic Mass223.061 Da
Topological Polar Surface Area107.000 Ų
Heavy Atom Count14
Formal Charge0
Complexity263.000
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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View related series

GluN2A Antagonist (13) GluN2B Antagonist (14) GluN2C Antagonist (13) GluN2D Antagonist (12) Ion channel (4039)
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