CH-0793076 TFA - ≥98% , CAS No.C659020

CAS: C659020 Cat. No.: C659020 Formula: C₂₈H₂₇F₃N₄O₆ Molecular Weight: 572.53

GRADE & PURITY ≥98%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Overview

CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC 50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resist

Appearance:Solid

IC50& Target:Topoisomerase I 2.3 μM (IC 50 )

In Vitro:CH0793076 (TP3076) TFA (6 days at 37°C) shows antiproliferative activity against PC-6/BCRP and PC-6/pRC cells, with IC 50 s of 0.35 and 0.18 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference o

Biological Activity:CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC 50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resist

Specifications

Specifications & Purity

≥98%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

Molecular Weight

572.53

Chemical and Physical Properties

• Solubility: DMSO : 30 mg/mL (52.40 mM; Need ultrasonic)