Chicago Sky Blue 6B - Moligand™,10mM in DMSO , CAS No.2610-05-1

CAS: 2610-05-1 Cat. No.: C422918 Molecular Weight: 992.79 EC Number: 220-026-8

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

Chicago Sky Blue 6B|2610-05-1|Direct Blue 1|Chicago Sky Blue|Chicago Blue 6B|Pontamine sky blue|C.I. Direct Blue 1|Sky Blue 6B|Tertrodirect Blue FF|Pontamine Sky Blue 6BX|Direct Sky Blue 6B|Niagara Sky Blue 6B|BRILLANT BENZO BLUE 6BA|Direct Blue FF|Azocar

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Chicago Sky Blue 6B is a counterstain of background autofluorescence in fluorescence and immunofluorescence histochemistry. It is also used as the filler of glass pipette electrode for electrophysiological recording of rat brain slices.

Specifications

Synonyms

Chicago Sky Blue 6B | 2610-05-1 | Direct Blue 1 | Chicago Sky Blue | Chicago Blue 6B | Pontamine sky blue | C.I. Direct Blue 1 | Sky Blue 6B | Tertrodirect Blue FF | Pontamine Sky Blue 6BX | Direct Sky Blue 6B | Niagara Sky Blue 6B | BRILLANT BENZO BLUE 6BA | Direct Blue FF | Azocar

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

Counterstain for background autofluorescence. Allosteric MIF inhibitor. VGLUT inhibitor. Inhibits MIF-directed proinflammatory activity. Potently inhibits L-glutamate uptake into synaptic vesicles. Shows central effects in vivo.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Names and Identifiers

• Canonical Smiles: COC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(C4=C(C=C3)C(=CC(=C4N)S(=O)(=O)[O-])S(=O)(=O)[O-])O)OC)N=NC5=C(C6=C(C=C5)C(=CC(=C6N)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+].[Na+].[Na+]
• IUPAC Name: tetrasodium;4-amino-6-[[4-[4-[(8-amino-1-hydroxy-5,7-disulfonatonaphthalen-2-yl)diazenyl]-3-methoxyphenyl]-2-methoxyphenyl]diazenyl]-5-hydroxynaphthalene-1,3-disulfonate
• InChIKey: BPHHNXJPFPEJOF-UHFFFAOYSA-J
• INCHI: 1S/C34H28N6O16S4.4Na/c1-55-23-11-15(3-7-19(23)37-39-21-9-5-17-25(57(43,44)45)13-27(59(49,50)51)31(35)29(17)33(21)41)16-4-8-20(24(12-16)56-2)38-40-22-10-6-18-26(58(46,47)48)14-28(60(52,53)54)32(36)30(18)34(22)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4
• Isomeric SMILES: COC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(C4=C(C=C3)C(=CC(=C4N)S(=O)(=O)[O-])S(=O)(=O)[O-])O)OC)N=NC5=C(C6=C(C=C5)C(=CC(=C6N)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+].[Na+].[Na+]
• Molecular Weight: 992.79
• Reaxy-Rn: 741774
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=741774&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Biphenyls and derivatives
        • Level5 Benzidines
          • Level6 3,3'-disubstituted benzidines

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Biphenyls and derivatives
• Intermediate Tree Nodes: Benzidines
• Direct Parent: 3,3'-disubstituted benzidines
• Alternative Parents: 1-naphthalene sulfonates 1-naphthalene sulfonic acids and derivatives 2-naphthalene sulfonates 2-naphthalene sulfonic acids and derivatives 1-sulfo,2-unsubstituted aromatic compounds Methoxyanilines Phenoxy compounds Anisoles Methoxybenzenes Phenoxides Alkyl aryl ethers Organosulfonic acids Sulfonyls Azo compounds Propargyl-type 1,3-dipolar organic compounds Hydrocarbon derivatives Organic sodium salts Primary amines Organic oxides Organic cations
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: 3,3'-disubstituted benzidine - Naphthalene sulfonate - 1-naphthalene sulfonic acid or derivatives - 2-naphthalene sulfonic acid or derivatives - Naphthalene sulfonic acid or derivatives - 1-naphthalene sulfonate - 2-naphthalene sulfonate - Naphthalene - Arylsulfonic acid or derivatives - 1-sulfo,2-unsubstituted aromatic compound - Methoxyaniline - Phenol ether - Methoxybenzene - Anisole - Phenoxy compound - Phenoxide - Alkyl aryl ether - Organic sulfonic acid or derivatives - Sulfonyl - Organosulfonic acid or derivatives - Organosulfonic acid - Azo compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Ether - Organic alkali metal salt - Organic nitrogen compound - Amine - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic salt - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic cation - Aromatic homopolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 3,3'-disubstituted benzidines. These are organic compounds containing a benzidine skeleton, which is substituted only at the 3- and 3'-positions.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 992.800 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 22
• Rotatable Bond Count: 7
• Exact Mass: 991.972 Da
• Monoisotopic Mass: 991.972 Da
• Topological Polar Surface Area: 423.000 Ų
• Heavy Atom Count: 64
• Formal Charge: 0
• Complexity: 1830.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 5

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