Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis . Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth .
| Isomeric SMILES | C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)OC(=O)CCC(=O)O)C)C |
|---|---|
| Molecular Weight | 486.74 |
| Reaxy-Rn | 3502962 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3502962&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Specific Rotation[α] | -34° (C=2,CHCl3) |
|---|---|
| Melt Point(°C) | 178℃ |
| 1. Pengyu Li, Jieyi Pan, Yating Dong, Yingying Sun, Yalong Wang, Kang Liao, Yili Chen, Xin Deng, Shihui Yu, Haiyan Hu. (2023) Microenvironment responsive charge-switchable nanoparticles act on biofilm eradication and virulence inhibition for chronic lung infection treatment. JOURNAL OF CONTROLLED RELEASE, [PMID:37992874] [10.1016/j.jconrel.2023.11.032] |
| 2. Jingjing Chai, Jiawei Hu, Tao Wang, Xing Bao, Jiajie Luan, Yan Wang. (2023) A Multifunctional Liposome for Synergistic Chemotherapy with Ferroptosis Activation of Triple-Negative Breast Cancer. MOLECULAR PHARMACEUTICS, [PMID:38153044] [10.1021/acs.molpharmaceut.3c00903] |
| 3. Di Chuan, Rangrang Fan, Bo Chen, Yangmei Ren, Min Mu, Haifeng Chen, Bingwen Zou, Haohao Dong, Aiping Tong, Gang Guo. (2023) Lipid–Polymer Hybrid Nanoparticles with Both PD-L1 Knockdown and Mild Photothermal Effect for Tumor Photothermal Immunotherapy. ACS Applied Materials & Interfaces, [PMID:37605506] [10.1021/acsami.3c07648] |
| 4. Yuan Lin, Yimin Zhang, Zhuang Xiong, Min Wu, Muling Zeng, Chuangnan Li, Fujin Liu, Yazhi Liao, Chunping Liu, Jing Chen. (2023) Development of glycyrrhetinic acid ligand-functionalized liposomes for targeting hepatocellular carcinoma: Synthesis, preparation, characterization, and evaluation. Arabian Journal of Chemistry, [PMID:] [10.1016/j.arabjc.2023.105131] |
| 5. Mengjun Zhang, Huiyang Jiang, Lan Wu, Haoyu Lu, Hriday Bera, Xing Zhao, Xiong Guo, Xulu Liu, Dongmei Cun, Mingshi Yang. (2022) Airway epithelial cell-specific delivery of lipid nanoparticles loading siRNA for asthma treatment. JOURNAL OF CONTROLLED RELEASE, [PMID:36265740] [10.1016/j.jconrel.2022.10.020] |
| 6. Lina Zhang, Yutao Jia, Han Hao, Mi Wang, Jing Wang. (2022) Mitochondria-targeted liposome-enveloped covalent organic framework co-delivery system for enhanced tumor therapy. MICROPOROUS AND MESOPOROUS MATERIALS, [PMID:] [10.1016/j.micromeso.2022.112198] |
| 7. Taiying Chen, Ngalei Tam, Yu Mao, Chengjun Sun, Zekang Wang, Yuchen Hou, Wuzheng Xia, Jia Yu, Linwei Wu. (2022) A multi-hit therapeutic nanoplatform for hepatocellular carcinoma: Dual stimuli-responsive drug release, dual-modal imaging, and in situ oxygen supply to enhance synergistic therapy. Materials Today Bio, [PMID:35847375] [10.1016/j.mtbio.2022.100338] |
| 8. Miaomiao Qi, Xiang Liu, Ying Zhou, Haoyu Wang, Ying Zhao, Jing Ren, Jin Xiang. (2021) Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (21): (11466). [PMID:34768896] [10.3390/ijms222111466] |
| 9. Yi Chen, Qianming Du, Qianqian Guo, Jing Huang, Lina Liu, Xiangchun Shen, Jianqing Peng. (2018) A W/O emulsion mediated film dispersion method for curcumin encapsulated pH-sensitive liposomes in the colon tumor treatment. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, [PMID:30346842] [10.1080/03639045.2018.1539099] |
| 10. Jie Wang, Xuemei Gu, Xia Gao, Jing Chen, Zhiyang Lv, Siyu Zhang, Siyu Ni, Fei Shi, Xialin Chen, Liang Cao, Zhenzhong Wang, Wei Xiao. (2025) Formulation and optimization of glycyrrhetinic acid-modified pH-sensitive curcumin liposomes for anti-hepatocellular carcinoma. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, [PMID:39935270] [10.1080/10837450.2025.2465549] |
| 11. Yanan Yang, Shuoye Yang, Beibei Zhang, Jinpeng Wang, Di Meng, Lan Cui, Lu Zhang. (2024) Hybrid Liposome-MSN System with Co-Delivering Potential Effective Against Multidrug-Resistant Tumor Targets in Mice Model. International Journal of Nanomedicine, [PMID:39246424] [10.2147/IJN.S472276] |
| 12. Yujun Chen, Mao Xu, Jieyi Pan, Yuan Liao, Jintong Na, Pengyu Li, Yingying Sun, Shihui Yu, Yongxiang Zhao, Haiyan Hu. (2025) Moxifloxacin-Loaded Polymeric Nanoparticles for Overcoming Multidrug Resistance in Chronic Pulmonary Infections Caused by Pseudomonas aeruginosa. ACS Applied Materials & Interfaces, [PMID:39804842] [10.1021/acsami.4c14991] |
| 13. Yuxin Zhao, Kai Liu, Chunmei Yan, Nini Luo, Huan Gu, Long Xie, Xiaofang Li. (2025) High-Density Lipoprotein Nanoparticles Loaded with Silybin for Therapy of Drug-Induced Liver Injury. ACS Applied Nano Materials, [PMID:] [10.1021/acsanm.5c01388] |
| 14. Jianying Ye, Yan Zhao, Baoyue Zhang, Shuo Li, Jinbo Li, Jiang Yu, Hongzhuo Liu, Yongjun Wang. (2026) Galloyl-Mediated Antigen Capture Coupled with Hypoxia-Responsive Reprogramming Drives Potent Photoimmunotherapy. ACS Nano, [PMID:41702861] [10.1021/acsnano.5c18030] |
| 15. Ying He, Nengbin Wan, Hongwu Deng, Yi Zhang, Qiang Liu, Li Li, Hao Liu, Xiao He, Qing Zhu. (2026) cRGD-modified, pH-sensitive liposomes for co-delivery of docetaxel and ABCG2 siRNA enhance therapeutic efficacy in triple-negative breast cancer. COLLOIDS AND SURFACES B-BIOINTERFACES, [PMID:] [10.1016/j.colsurfb.2026.115616] |
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