CUDA - ≥95% , CAS No.479413-68-8

CAS: 479413-68-8 Cat. No.: C346200 Formula: C₁₉H₃₆N₂O₃ Molecular Weight: 340.50

GRADE & PURITY ≥95%

Synonyms

12-(cyclohexylcarbamoylamino)dodecanoic acid | HY-121538 | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid | DTXSID60629291 | SR-01000946808-1 | HMS3650M07 | CHEBI:181802 | BDBM129262 | US8815951, 425 | SR-01000946808 | 12-[(CYCLOHEXYLCARBAMOYL)AMIN

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

CUDA is an inhibitor of soluble epoxide hydrolase (sEH, IC|50|= 11.1 nM in mice). Studies have shown that 10 μM of CUDA can block the conversion of 14,15-EET to 14,15-DHET by 94% in COS-7 cells. CUDA selectively activates peroxisome proliferator-activated receptor α (PPARα) 8-fold at a concentration of 10 μM with no affect on PPARδ or PPARγ.CUDA may be valuable for the study of cardiovascular diseases.

Specifications

Synonyms

12-(cyclohexylcarbamoylamino)dodecanoic acid | HY-121538 | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid | DTXSID60629291 | SR-01000946808-1 | HMS3650M07 | CHEBI:181802 | BDBM129262 | US8815951, 425 | SR-01000946808 | 12-[(CYCLOHEXYLCARBAMOYL)AMIN

Specifications & Purity

≥95%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ACTIVATOR

Purity

≥95%

Names and Identifiers

Pubchem Sid

528763833

Canonical Smiles

C1CCC(CC1)NC(=O)NCCCCCCCCCCCC(=O)O

IUPAC Name

12-(cyclohexylcarbamoylamino)dodecanoic acid

InChIKey

HPTJABJPZMULFH-UHFFFAOYSA-N

INCHI

1S/C19H36N2O3/c22-18(23)15-11-6-4-2-1-3-5-7-12-16-20-19(24)21-17-13-9-8-10-14-17/h17H,1-16H2,(H,22,23)(H2,20,21,24)

Isomeric SMILES

C1CCC(CC1)NC(=O)NCCCCCCCCCCCC(=O)O

Molecular Weight

340.50

Reaxy-Rn

9358961

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9358961&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Fatty Acyls
      • Subclass Fatty acids and conjugates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Fatty Acyls
• Subclass: Fatty acids and conjugates
• Intermediate Tree Nodes: Not available
• Direct Parent: Medium-chain fatty acids
• Alternative Parents: Amino fatty acids Ureas Monocarboxylic acids and derivatives Carboxylic acids Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: Medium-chain fatty acid - Amino fatty acid - Urea - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as medium-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

EPHX1 Tchem Epoxide hydrolase 1 (1 Activities)

Discover Target: EPHX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Chemical and Physical Properties

• Molecular Weight: 340.500 g/mol
• XLogP3: 5.000
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 13
• Exact Mass: 340.273 Da
• Monoisotopic Mass: 340.273 Da
• Topological Polar Surface Area: 78.400 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 342.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1