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CYM50358 - ≥98% , CAS No.1314212-39-9

CAS: 1314212-39-9 Cat. No.: C649203 Molecular Weight: 389.28 EC Number: 808-352-4 PubChem CID: 53358422
COA
CYM50358 - ≥98% CAS No(1314212-39-9) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
EX-A5683 | GTPL10312 | CYM 50358 | N-(4-(aminomethyl)-2,6-dimethylphenyl)-5-(2,5-dichlorophenyl)furan-2-carboxamide | AKOS040759830 | HY-136462 | NCGC00379182-01 | NCGC00379182-03 | CYM50358, >=98% (HPLC) | NCGC00379182-02 | CYM50358 | CYM-50358 | MS-2646
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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C649203-5mg
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

CYM50358 is a potent and selective S1PR4 antagonist, with an IC 50 of 25 nM. CYM50358 can be used for the research of influenza infection

In Vitro

CYM50358 shows less potent inhibition of S1PR1 (IC 50 =6.4 μM). CYM50358 (10 μM) has no effect on the collagen-induced HSP27 phosphorylation, markedly reverses the suppressive effect of S1P on the collagen-induced phosphorylation of HSP27. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:S1PR4 25 nM (IC 50 )

Specifications

Synonyms
EX-A5683 | GTPL10312 | CYM 50358 | N-(4-(aminomethyl)-2, 6-dimethylphenyl)-5-(2, 5-dichlorophenyl)furan-2-carboxamide | AKOS040759830 | HY-136462 | NCGC00379182-01 | NCGC00379182-03 | CYM50358, >=98% (HPLC) | NCGC00379182-02 | CYM50358 | CYM-50358 | MS-2646
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
CYM50358 is a potent and selective S1PR4 antagonist, with an IC 50 of 25 nM. CYM50358 can be used for the research of influenza infection.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ANTAGONIST
Purity
≥98%
Names and Identifiers
Canonical SmilesCC1=CC(=CC(=C1NC(=O)C2=CC=C(O2)C3=C(C=CC(=C3)Cl)Cl)C)CN
IUPAC NameN-[4-(aminomethyl)-2,6-dimethylphenyl]-5-(2,5-dichlorophenyl)furan-2-carboxamide
InChIKeyQWJOPXDAQCDRRM-UHFFFAOYSA-N
INCHI1S/C20H18Cl2N2O2/c1-11-7-13(10-23)8-12(2)19(11)24-20(25)18-6-5-17(26-18)15-9-14(21)3-4-16(15)22/h3-9H,10,23H2,1-2H3,(H,24,25)
Isomeric SMILES CC1=CC(=CC(=C1NC(=O)C2=CC=C(O2)C3=C(C=CC(=C3)Cl)Cl)C)CN
WGK Germany 3
PubChem CID 53358422
Molecular Weight 389.28

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassAnilides
Intermediate Tree Nodes Aromatic anilides - Furanilides
Direct Parent2-furanilides
Alternative Parents m-Xylenes  Phenylmethylamines  2-heteroaryl carboxamides  Benzylamines  Furoic acid and derivatives  Dichlorobenzenes  Aralkylamines  Aryl chlorides  Heteroaromatic compounds  Secondary carboxylic acid amides  Amino acids and derivatives  Oxacyclic compounds  Hydrocarbon derivatives  Monoalkylamines  Organic oxides  Organochlorides  Organooxygen compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents 2-furanilide - 2-heteroaryl carboxamide - Furoic acid or derivatives - 1,4-dichlorobenzene - M-xylene - Xylene - Benzylamine - Phenylmethylamine - Halobenzene - Chlorobenzene - Aralkylamine - Aryl chloride - Aryl halide - Heteroaromatic compound - Furan - Secondary carboxylic acid amide - Carboxamide group - Amino acid or derivatives - Carboxylic acid derivative - Organoheterocyclic compound - Oxacycle - Amine - Primary aliphatic amine - Organohalogen compound - Organochloride - Organonitrogen compound - Organooxygen compound - Primary amine - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as 2-furanilides. These are aromatic heterocyclic compounds contaning a furan ring that is substituted at the 2-position with an anilide.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
S1PR4 Tclin Sphingosine 1-phosphate receptor 4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
S1PR4 Tclin Sphingosine 1-phosphate receptor Edg-6 (1041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
S1PR3 Tclin Sphingosine 1-phosphate receptor Edg-3 (2543 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
S1PR2 Tchem Sphingosine 1-phosphate receptor Edg-5 (1593 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
S1PR1 Tclin Sphingosine 1-phosphate receptor Edg-1 (5806 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
S1PR5 Tclin Sphingosine 1-phosphate receptor Edg-8 (813 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilityDMSO : 125 mg/mL (321.11 mM; Need ultrasonic)
Molecular Weight389.300 g/mol
XLogP34.700
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass388.075 Da
Monoisotopic Mass388.075 Da
Topological Polar Surface Area68.300 Ų
Heavy Atom Count26
Formal Charge0
Complexity480.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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