≥98.5% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biorenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks".Click herefor more information.Cyrene is a biobased dipolar, aprotic alternative to common solvents that are of environmental concern. Cyrene is an alternative for many solvents classified by REACH as Substances of Very High Concern (SVHC), such as N-Methylpyrorrolidone (NMP) and Dimethylformamide (DMF).In testing, Cyrene has shown to behave similarly to NMP with minimal loss in performance in heteroatom alkylation and nucleophilic fluorination reactions.Cyrene has been demonstrated to exceed NMP′s dispersive ability for graphene solutions. Graphene concentrations in Cyrene are an order of magnitude greater than with NMP due to its optimum polarity and high viscosity, creating larger and less defective graphene flakes.
| Canonical Smiles | C1CC(=O)C2OCC1O2 |
|---|---|
| IUPAC Name | (1S,5R)-6,8-dioxabicyclo[3.2.1]octan-4-one |
| InChIKey | WHIRALQRTSITMI-UJURSFKZSA-N |
| INCHI | 1S/C6H8O3/c7-5-2-1-4-3-8-6(5)9-4/h4,6H,1-3H2/t4-,6+/m0/s1 |
| Isomeric SMILES | C1CC(=O)[C@@H]2OC[C@H]1O2 |
| Molecular Weight | 128.13 |
| Reaxy-Rn | 26856616 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=26856616&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Oxepanes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Oxepanes |
| Alternative Parents | Oxanes 1,3-dioxolanes Ketones Oxacyclic compounds Acetals Organic oxides Hydrocarbon derivatives Aldehydes |
| Molecular Framework | Aliphatic heteropolycyclic compounds |
| Substituents | Oxepane - Oxane - Meta-dioxolane - Ketone - Oxacycle - Acetal - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aldehyde - Aliphatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as oxepanes. These are compounds containing an oxepane ring, which is a seven-member saturated aliphatic heterocycle with one oxygen and six carbon atoms. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2631229 | Certificate of Analysis | Mar 21, 2026 | C478499 |
| C2631230 | Certificate of Analysis | Mar 21, 2026 | C478499 |
| C2631231 | Certificate of Analysis | Mar 21, 2026 | C478499 |
| J2517660 | Certificate of Analysis | Oct 11, 2025 | C478499 |
| J2517659 | Certificate of Analysis | Oct 11, 2025 | C478499 |
| J2517657 | Certificate of Analysis | Oct 11, 2025 | C478499 |
| G2501302 | Certificate of Analysis | Mar 25, 2025 | C478499 |
| G2501301 | Certificate of Analysis | Mar 25, 2025 | C478499 |
| G2501300 | Certificate of Analysis | Mar 25, 2025 | C478499 |
| A2506086 | Certificate of Analysis | Dec 28, 2024 | C478499 |
| A2506420 | Certificate of Analysis | Dec 28, 2024 | C478499 |
| A2506085 | Certificate of Analysis | Dec 28, 2024 | C478499 |
| G2408538 | Certificate of Analysis | Jun 28, 2024 | C478499 |
| G2408537 | Certificate of Analysis | Jun 28, 2024 | C478499 |
| G2408536 | Certificate of Analysis | Jun 28, 2024 | C478499 |
| G2408535 | Certificate of Analysis | Jun 28, 2024 | C478499 |
| D2409071 | Certificate of Analysis | Dec 08, 2023 | C478499 |
| C2426008 | Certificate of Analysis | Dec 08, 2023 | C478499 |
| L2314159 | Certificate of Analysis | Dec 08, 2023 | C478499 |
| L2314160 | Certificate of Analysis | Dec 08, 2023 | C478499 |
| L2314161 | Certificate of Analysis | Dec 08, 2023 | C478499 |
| L2314162 | Certificate of Analysis | Dec 08, 2023 | C478499 |
| L2314183 | Certificate of Analysis | Dec 08, 2023 | C478499 |
| Boil Point(°C) | 227 °C |
|---|---|
| Melt Point(°C) | -18 °C |
| Molecular Weight | 128.130 g/mol |
| XLogP3 | -0.200 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 128.047 Da |
| Monoisotopic Mass | 128.047 Da |
| Topological Polar Surface Area | 35.500 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 143.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jiao Chen, Chunyan Li, Dongjie Liao, Xing Yan, Chongwei An. (2024) Dissolution Properties Of Energetic Materials In The Environmentally Friendly Solvent Cyrene. Journal of Energetic Materials, [PMID:] [10.1080/07370652.2024.2446887] |
