DBCO-PEG4-GGFG-Exatecan - ≥98% , CAS No.2694856-51-2

CAS: 2694856-51-2 Cat. No.: D646155 Molecular Weight: 1375.45

GRADE & PURITY ≥98%

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

DBCO-PEG4-GGFG-Exatecan (DBCO-PEG4-GGFG-DX8951) is a agent-linker conjugate for ADC with potent antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linke. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Traditional Cytotoxic Agents

Specifications

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

DBCO-PEG4-GGFG-Exatecan (DBCO-PEG4-GGFG-DX8951) is a agent-linker conjugate for ADC with potent antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG.

Storage

Protected from light, Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: O=C1OCC2=C(C=C(C3=NC4=CC(F)=C(C)C(CC[C@@H]5NC(COCNC(CNC([C@H](CC6=CC=CC=C6)NC(CNC(CNC(CCOCCOCCOCCOCCNC(CCC(N7C8=CC=CC=C8C#CC9=CC=CC=C9C7)=O)=O)=O)=O)=O)=O)=O)=O)=C4C5=C3C%10)N%10C2=O)[C@]1(CC)O
• Molecular Weight: 1375.45

Chemical and Physical Properties

• Solubility: DMSO : 50 mg/mL (36.35 mM; ultrasonic and warming and heat to 60°C)