ddTTP (10mM) - BioReagent, DNase, RNase free, PCR Reagent, Suitable for molecular biology, sterile, for DNA and RNA applications, ≥99%, 10mM , CAS No.611-60-9

CAS: 611-60-9 Cat. No.: T759812 Molecular Weight: 532.11

GRADE & PURITY Suitable for molecular biology, BioReagent, DNase, RNase free, PCR Reagent, Sterile, for DNA and RNA applications, ≥99%, 10mM

Synonyms

2',3'-Dideoxythymidine 5'-triphosphate | ddTTP

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Overview

ddTTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. This product is a dideoxynucleotide that serves as a chain-terminating inhibitor of DNA polymerase, is a primary substrate for nucleic acid mass spectrometry kits, and can also be used for Sanger sequencing.

Specifications

Synonyms

2', 3'-Dideoxythymidine 5'-triphosphate | ddTTP

Specifications & Purity

BioReagent, DNase, RNase free, PCR Reagent, Suitable for molecular biology, sterile, for DNA and RNA applications, ≥99%, 10mM

Stability And Storage

Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Storage

Store at -20°C, Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

BioReagent, DNase, RNase free, for DNA and RNA applications, PCR Reagent, Sterile, Suitable for molecular biology

Purity

≥99%

Names and Identifiers

• PH: 9.0-10.0
• Canonical Smiles: CC1=CN(C(=O)NC1=O)C2CCC(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O
• IUPAC Name: [hydroxy-[[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate
• InChIKey: URGJWIFLBWJRMF-JGVFFNPUSA-N
• INCHI: 1S/C10H17N2O13P3/c1-6-4-12(10(14)11-9(6)13)8-3-2-7(23-8)5-22-27(18,19)25-28(20,21)24-26(15,16)17/h4,7-8H,2-3,5H2,1H3,(H,18,19)(H,20,21)(H,11,13,14)(H2,15,16,17)/t7-,8+/m0/s1
• Isomeric SMILES: CC1=CN(C(=O)NC1=O)[C@H]2CC[C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O
• Molecular Weight: 532.11

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class Pyrimidine nucleotides
      • Subclass Pyrimidine deoxyribonucleotides
        • Level5 Pyrimidine deoxyribonucleoside triphosphates
          • Level6 Pyrimidine 2',3'-dideoxyribonucleoside triphosphates

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: Pyrimidine nucleotides
• Subclass: Pyrimidine deoxyribonucleotides
• Intermediate Tree Nodes: Pyrimidine deoxyribonucleoside triphosphates
• Direct Parent: Pyrimidine 2',3'-dideoxyribonucleoside triphosphates
• Alternative Parents: Pyrimidones Monoalkyl phosphates Hydroxypyrimidines Hydropyrimidines Tetrahydrofurans Heteroaromatic compounds Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Pyrimidine 2',3'-dideoxyribonucleoside triphosphate - Pyrimidone - Monoalkyl phosphate - Hydroxypyrimidine - Hydropyrimidine - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Alkyl phosphate - Tetrahydrofuran - Heteroaromatic compound - Organoheterocyclic compound - Azacycle - Oxacycle - Organopnictogen compound - Organooxygen compound - Organic oxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as pyrimidine 2',3'-dideoxyribonucleoside triphosphates. These are pyrimidine nucleotides with triphosphate group linked to the ribose moiety lacking a hydroxyl group at positions 2 and 3.
• External Descriptors: thymidine phosphate - pyrimidine 2',3'-dideoxyribonucleoside 5'-triphosphate

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y