(-)-devapamil - Moligand™ , Gating inhibitor of Ca v1.2, CAS No.D609845, Gating inhibitor of Ca v1.2

CAS: D609845 Cat. No.: D609845 PubChem CID: 107928

GRADE & PURITY Moligand™

Synonyms

(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3-methoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile|DEVAPAMIL, (-)-|DESMETHOXYVERAPAMIL, (-)-|Benzeneacetonitrile, 3,4-dimethoxy-alpha-(3-((2-(3-methoxyphenyl)ethyl)methylamino)propyl)-alpha-(1-methylethyl)-, (S)-|(-)-Desmethoxyverapamil|(-)-Devapamil|(alphaS)-3,4-Dimethoxy-alpha-[3-[[2-(3-methoxyphenyl)ethyl]methylamino]propyl]-alpha-(1-methylethyl)benzeneacetonitrile|Benzeneacetonitrile, 3,4-dimethoxy-alpha-(3-((2-(3-methoxyphenyl)ethyl)methylamino)propyl)-alpha-(1-methylethyl)-, (-)-|[3H](-)devapamil|BENZENEACETONITRILE, 3,4-DIMETHOXY-.ALPHA.-(3-((2-(3-METHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-.ALPHA.-(1-METHYLETHYL)-, (S)-|BENZENEACETONITRILE, 3,4-DIMETHOXY-.ALPHA.-(3-((2-(3-METHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-.ALPHA.-(1-METHYLETHYL)-, (.ALPHA.S)-|4-DMV|4-desmethoxyverapamil (4-DMV)|(-)-H3-Desmethoxyverapamil|4-Desmethoxyverapamil

Storage

Room temperature

Specifications

Synonyms

(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3-methoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile | DEVAPAMIL, (-)- | DESMETHOXYVERAPAMIL, (-)- | Benzeneacetonitrile, 3,4-dimethoxy-alpha-(3-((2-(3-methoxyphenyl)ethyl)methylamino)propyl)-alpha-(1-methylethyl)-, (S)- | (-)-Desmethoxyverapamil | (-)-Devapamil | (alphaS)-3,4-Dimethoxy-alpha-[ Show more

Specifications & Purity

Moligand™

Storage

Room temperature

Grade

Moligand™

Action Type

GATING INHIBITOR

Mechanism of action

Gating inhibitor of Ca v1.2

Names and Identifiers

Canonical Smiles

COc1cccc(c1)CCN(CCC[C@@](c1ccc(c(c1)OC)OC)(C(C)C)C#N)C

IUPAC Name

(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3-methoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile

InChIKey

VMVKIDPOEOLUFS-SANMLTNESA-N

INCHI

1S/C26H36N2O3/c1-20(2)26(19-27,22-11-12-24(30-5)25(18-22)31-6)14-8-15-28(3)16-13-21-9-7-10-23(17-21)29-4/h7,9-12,17-18,20H,8,13-16H2,1-6H3/t26-/m0/s1

Isomeric SMILES

CC(C)[C@](CCCN(C)CCC1=CC(=CC=C1)OC)(C#N)C2=CC(=C(C=C2)OC)OC

PubChem CID

107928

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Phenylbutylamines

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Phenylbutylamines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylbutylamines
• Alternative Parents: Phenylpropanes Phenethylamines Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers Trialkylamines Nitriles Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Phenylbutylamine - Phenylpropane - Phenethylamine - Phenoxy compound - Methoxybenzene - Phenol ether - Anisole - Alkyl aryl ether - Tertiary aliphatic amine - Tertiary amine - Nitrile - Carbonitrile - Ether - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as phenylbutylamines. These are compounds containing a phenylbutylamine moiety, which consists of a phenyl group substituted at the fourth carbon by an butan-1-amine.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CACNA1C Tclin Voltage-dependent L-type calcium channel subunit alpha-1C (1 Activities)

Discover Target: CACNA1C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Frequently Asked Questions

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is D609845. InChIKey VMVKIDPOEOLUFS-SANMLTNESA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.