Dextran, used for Dextran has been used as a polymer standard in the quantitative determination of intracellular sodium [Na+] using fluorescence lifetime imaging microscopy (FLIM) with CoroNaGreen dye.It has also been used in combination with concanavalin

CAS: 9004-54-0 Cat. No.: D491543 Formula: [C₆H₁₀O₅]_n Molecular Weight: 270000 EC Number: 232-677-5

Synonyms

Dextran 40 | Macrodex | Dextran T40 | 6-O-(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)-D-glucose | DEXTRAN | Dextran 70 | 2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal

Storage

Room temperature,Argon charged,Desiccated

Shipped In

Normal

Overview

Dextran a multi-use, branched glucan with long, hydrophilic spacer arms that improve the performance of immobilized proteins acting on macromolecules. Low molecular weight dextran is useful as a stabilizer, volume extender, lubricant, binding platform, and matrix component. Higher molecular weight dextrans have differing viscosities, aggregation and permeation properties.
A multi-use, branched glucan

Dextran (mol. wt. 80,000) belongs to the family of neutral polysaccharides,which are recognized as contaminants in sugar processing and other food production industries. These are composed of chains of D-glucose units connected by alpha-(1-6) linkages of varying lengths.They are found as bacterial extracellular polysaccharides and reportedly synthesized from sucrose by beneficial lactic acid bacteria, such as Leuconostoc mesenteroides and Lactobacillus brevis. They are incorporated in bakery products to improve the crumb texture, softness, and loaf volume, as stabilizers and additives in confectionery, flavor extract, icing compositions, beverages including soft drinks, milk, etc.
Product specifications and parameters

sku	Name	Molecular Weight
D491543-1000	Dextran	1000
D491543-12K	Dextran	12000
D491543-150K	Dextran	150000
D491543-25K	Dextran	25000
D491543-270K	Dextran	270000
D491543-410K	Dextran	410000
D491543-5000	Dextran	5000
D491543-50K	Dextran	50000
D491543-670K	Dextran	670000
D491543-80K	Dextran	80000
D491543-2000K	Dextran	2000000
D491543-3800K	Dextran	3800000
D491543-5400K	Dextran	5400000

Specifications

Synonyms

Dextran 40 | Macrodex | Dextran T40 | 6-O-(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)-D-glucose | DEXTRAN | Dextran 70 | 2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal

Application

Dextran has been used as a polymer standard in the quantitative determination of intracellular sodium [Na+] using fluorescence lifetime imaging microscopy (FLIM) with CoroNaGreen dye.It has also been used in combination with concanavalin A as concanavalin

Storage

Room temperature,Argon charged,Desiccated

Shipped In

Normal

Names and Identifiers

Pubchem Sid

508816515

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508816515

Canonical Smiles

C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC(C(C(C(C=O)O)O)O)O)O)O)O)O)O)O)O

IUPAC Name

2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal

InChIKey

FZWBNHMXJMCXLU-UHFFFAOYSA-N

INCHI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

Isomeric SMILES

C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC(C(C(C(C=O)O)O)O)O)O)O)O)O)O)O)O

WGK Germany

2

Molecular Weight

270000

Reaxy-Rn

30920174

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30920174&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Fatty Acyls
      • Subclass Fatty acyl glycosides

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Fatty Acyls
• Subclass: Fatty acyl glycosides
• Intermediate Tree Nodes: Not available
• Direct Parent: Fatty acyl glycosides of mono- and disaccharides
• Alternative Parents: Alkyl glycosides O-glycosyl compounds Disaccharides Oxanes Beta-hydroxy aldehydes Alpha-hydroxyaldehydes Secondary alcohols Polyols Oxacyclic compounds Acetals Primary alcohols Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Fatty acyl glycoside of mono- or disaccharide - Alkyl glycoside - Disaccharide - Glycosyl compound - O-glycosyl compound - Beta-hydroxy aldehyde - Oxane - Alpha-hydroxyaldehyde - Secondary alcohol - Polyol - Acetal - Organoheterocyclic compound - Oxacycle - Organooxygen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organic oxygen compound - Aldehyde - Alcohol - Primary alcohol - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as fatty acyl glycosides of mono- and disaccharides. These are compounds composed of a mono- or disaccharide moiety linked to one hydroxyl group of a fatty alcohol or of a phosphorylated alcohol (phosphoprenols), a hydroxy fatty acid or to one carboxyl group of a fatty acid (ester linkage) or to an amino alcohol.
• External Descriptors: a small molecule

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: moisture sensitive
• Specific Rotation[α]: 197° (C=6,H2O)
• Molecular Weight: 504.400 g/mol
• XLogP3: -7.200
• Hydrogen Bond Donor Count: 11
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 11
• Exact Mass: 504.169 Da
• Monoisotopic Mass: 504.169 Da
• Topological Polar Surface Area: 277.000 Ų
• Heavy Atom Count: 34
• Formal Charge: 0
• Complexity: 625.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 14
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1