1000μg/ml,Matrix: methanol for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light Ships Wet ice,FedEx DG Service Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 35 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Application
It is used for quality assurance and quality control in environmental monitoring and analytical testing, and can also be used for instrument calibration, method verification and technical arbitration.
Sample Preparation
This standard substance uses dichloroacetic acid whose purity has been accurately determined as the solute and methanol as the solvent. It is prepared by the weight-volume method in a clean laboratory at room temperature of 20±3°C.
Traceability and valuation method
The concentration standard value of this standard substance adopts the prepared value, and the value is checked by gas chromatography. Through the use of preparation, measurement methods and measuring instruments that meet the requirements of metrology characteristics, the traceability of the quality value of the standard material is guaranteed.
Characteristic value and expanded uncertainty
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The expanded uncertainty of the standard value is mainly synthesized by the uncertainty of raw material purity, weighing, constant volume, uniformity, and long-term stability.
Packaging, storage and use
Packaging: This standard substance is packaged, and the specification 1.2ml should be protected against chipping when carried or transported. Storage and use: Keep refrigerated and protected from light. Before use, it should be balanced at room temperature (20±3℃) and shaken sufficiently to ensure uniformity. Once the ampoule is opened, it should be used immediately. It cannot be used as a standard substance after being re-sealed. Strictly prevent contamination during use.
| Isomeric SMILES | C(C(=O)O)(Cl)Cl |
|---|---|
| WGK Germany | 2 |
| RTECS | AG6125000 |
| UN Number | 1764 |
| Packing Group | II |
| Molecular Weight | 128.94 |
| Beilstein | 2202 |
| Reaxy-Rn | 1098596 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1098596&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Freezing Point(°C) | 13 °C |
|---|---|
| Refractive Index | 1.4659 |
| Flash Point(°C) | >112℃ |
| Boil Point(°C) | 193-194°C |
| Melt Point(°C) | 9.7°C |
| 1. Xin He, Hong-Xu Zhou, Xian Fu, Kai-Di Ni, Ai-Zhi Lin, Ling-Tong Zhang, Hou-Hua Yin, Qing Jiang, Xue Zhou, Yi-Wen Meng, Jun-Yan Liu. (2023) Metabolomics study reveals increased deoxycholic acid contributes to deoxynivalenol-mediated intestinal barrier injury. LIFE SCIENCES, [PMID:38016577] [10.1016/j.lfs.2023.122302] |
| 2. Chunge Wu, Yicui Wang, Xuewen Cai, Yao Wu, Erdeng Du, Lu Zheng, Mingguo Peng. (2023) Investigating haloacetic acids - human serum albumin interactions: A comprehensive approach using multi-spectroscopy, DFT calculations, and molecular docking. JOURNAL OF MOLECULAR STRUCTURE, [PMID:] [10.1016/j.molstruc.2023.137143] |
| 3. Fengming Zhao, Lili Zhao, Xinhang Wang, Huadong Hu, Yinghong Zhu, Youqun Chu, Wanli Chen. (2023) A Flexible Self-Supported Silver Wire with Nanoporous Skeleton for Electrochemical Sensing of Trichloroacetic Acid. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 170 (10): (106501). [PMID:] [10.1149/1945-7111/acfa25] |
| 4. Jiaben Zhong, Hangyan Zhang, Yina Cai, Xiuping Chen, Zhiyuan Fang, Dun Deng. (2023) Rapid and visual detection of dichloroacetonitrile in water. ANALYST, 148 (21): (5390-5394). [PMID:37750310] [10.1039/D3AN01282D] |
| 5. Junyan Wei, Shengnan Zhang, Ruixue Guo, Ahmed A. Allam, Jamaan S. Ajarem, Naif G. Altoom, Afzal Ahmed Dar, Ruijuan Qu, Zongli Huo, Feng Zhu. (2023) Transformation behavior of the ultraviolet absorbent 2-(2H-benzotriazol-2-yl)-4,6-di-tert-pentylphenol (UV328) in polyethylene plastic under chlorination. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2023.110759] |
| 6. Tianyu Zeng, Shuai Wu, Qizhi Liang, Hai Shi, Jue Gong, Ningjun Duan, Wei Li, Genxi Li, Yongmei Yin. (2023) A colorimetric biosensor to track Trop-2 status of tumor cells for diagnosis of breast cancer. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2023.134020] |
| 7. Xiaoyan Ma, Sinong Huang, Yuhong Jin, Hang Jiang, Liangjie Tang, Yifei Wu, Yongjiong Ni, Shijun Zhu, Xueyan Li, Andrea M. Dietrich. (2023) Electrocatalytic dechlorination of aqueous trichloroacetic acid by Vitamin B12 modified iron electrode. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2023.109944] |
| 8. Liying Zhang, Xiaodan Ma, Qian Li, Hanlin Cui, Ke Shi, Hao Wang, Yanqing Zhang, Shuhong Gao, Zhiling Li, Ai-Jie Wang, Bin Liang. (2023) Complementary Biotransformation of Antimicrobial Triclocarban Obviously Mitigates Nitrous Oxide Emission toward Sustainable Microbial Denitrification. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:37053517] [10.1021/acs.est.2c08732] |
| 9. Kaiyue Huo, Siqi Wang, Wanwan Zhao, Hongfu Guo, Weini Xiong, Ruihua Liu, Chao Yang. (2023) Creating an efficient 1,2-dichloroethane-mineralizing bacterium by a combination of pathway engineering and promoter engineering. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:37001652] [10.1016/j.scitotenv.2023.163140] |
| 10. Yao-Shen Guo, Cheng Chen, Chun-Er Lin, Li-Ping Zhu, Hong-Xing Liu. (2023) High-performance quaternized hollow fiber membrane with sponge pore structure for fast adsorbing dichloroacetic acid from water by flow-through adsorption. JOURNAL OF APPLIED POLYMER SCIENCE, 140 (12): (e53638). [PMID:] [10.1002/app.53638] |
| 11. Zhen Pang, Peifeng Zhang, Xinyi Chen, Feilong Dong, Jing Deng, Cong Li, Junping Liu, Xiaoyan Ma, Andrea M. Dietrich. (2022) Occurrence and modeling of disinfection byproducts in distributed water of a megacity in China: Implications for human health. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:35926603] [10.1016/j.scitotenv.2022.157674] |
| 12. Youqun Chu, Xinhang Wang, Lingqiao Wang, Zhaoyang Chen, Yinghong Zhu, Fengming Zhao. (2022) Electroanalytical sensing of trichloroacetic acid based on activated self-supported porous silver wire prepared by voltammetric etching with trichloroacetic acid as etchant. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, [PMID:] [10.1016/j.jelechem.2022.116601] |
| 13. Feilong Dong, Zhen Pang, Jianquan Yu, Jing Deng, Xueyan Li, Xiaoyan Ma, Andrea M. Dietrich, Yang Deng. (2021) Spatio-temporal variability of halogenated disinfection by-products in a large-scale two-source water distribution system with enhanced chlorination. JOURNAL OF HAZARDOUS MATERIALS, [PMID:34523488] [10.1016/j.jhazmat.2021.127113] |
| 14. Rongxiu Tu, Yujun Wang, Jinyun Peng, Chuantao Hou, Zonghua Wang. (2021) Integration of Multiple Redox Centers into Porous Coordination Networks for Ratiometric Sensing of Dissolved Oxygen. ACS Applied Materials & Interfaces, [PMID:34403589] [10.1021/acsami.1c13601] |
| 15. Wenjuan Zhu, Pingning Jin, Meng Cheng, Hongrui Yang, Mengmeng Du, Tiemei Li, Guifen Zhu, Jing Fan. (2021) Novel recyclable acidic hydrophobic deep eutectic solvents for highly efficient extraction of calcium dobesilate in water and urine samples. TALANTA, [PMID:34215026] [10.1016/j.talanta.2021.122523] |
| 16. Xiaofen Zhang, Ziyao Yang, Ziyu Shi, Zijia Zhu, Cai Li, Zhicheng Du, Yiding Zhang, Zipeng Wang, Zhenrui Jiao, Xin Tian, Ji Zhang, Wenlong Zhai, Quancheng Kan. (2020) Analysis of bile acid profile in plasma to differentiate cholangiocarcinoma from benign biliary diseases and healthy controls. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, [PMID:33130021] [10.1016/j.jsbmb.2020.105775] |
| 17. Gao Jie, Yuan Guanyin, Xu Zhan, Lan Luyao, Xin Wenkuan. (2020) Chenodeoxycholic and deoxycholic acids induced positive inotropic and negative chronotropic effects on rat heart. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 394 (4): (765-773). [PMID:32808070] [10.1007/s00210-020-01962-7] |
| 18. Ziheng Bai, Qi Liu, Hongsen Zhang, Jingyuan Liu, Jing Yu, Jun Wang. (2019) High efficiency biosorption of Uranium (VI) ions from solution by using hemp fibers functionalized with imidazole-4,5-dicarboxylic. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2019.111739] |
| 19. Gui-xin Zhang, Chen Zhan, Kai Wang, Jian Han, Dong Shang, Hai-long Chen. (2019) Qingyi Decoction amerliorates acute biliary pancreatitis by targeting Gpbar1/NF-kb pathway. Frontiers in Bioscience-Landmark, 24 (5): (833-848). [PMID:30844716] [10.2741/4754] |
| 20. Haoliang Cheng, Min Wang, Yaru Li, Guanyu Zhao, Zhong-Sheng Wang. (2019) An imidazolium iodide salt as a bifunctional co-adsorbent for quasi-solid-state dye-sensitized solar cells: improvements of electron lifetime and charge collection efficiency. Journal of Materials Chemistry A, 7 (6): (2702-2708). [PMID:] [10.1039/C8TA11333E] |
| 21. Yiqun Gan, Shengcun Ma, Xiaoqi Guo, Baiyang Chen, David Jassby. (2018) Photolysis of chloral hydrate in water with 254 nm ultraviolet: Kinetics, influencing factors, mechanisms, and products. CHEMOSPHERE, [PMID:30469001] [10.1016/j.chemosphere.2018.11.065] |
| 22. Rui Wang, Yi Xie, Tao Xiang, Shudong Sun, Changsheng Zhao. (2017) Direct catechol conjugation of mussel-inspired biomacromolecule coatings to polymeric membranes with antifouling properties, anticoagulant activity and cytocompatibility. Journal of Materials Chemistry B, 5 (16): (3035-3046). [PMID:32263995] [10.1039/C6TB03329F] |
| 23. Ying Hua Xu, Hong Zhang, Cheng Pu Chu, Chun An Ma. (2011) Dechlorination of chloroacetic acids by electrocatalytic reduction using activated silver electrodes in aqueous solutions of different pH. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, [PMID:] [10.1016/j.jelechem.2011.10.010] |
| 24. Yuwei Ye, Abudumijiti Abulizi, Yukun Zhang, Feng Lu, Yongpan An, Chaoqun Ren, Hang Zhang, Yiming Wang, Dongmei Lin, Dan Lu, Min Li, Baoxue Yang. (2025) Ganoderic Acid Ameliorates Ulcerative Colitis by Improving Intestinal Barrier Function via Gut Microbiota Modulation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 26 (6): (2466). [PMID:40141109] [10.3390/ijms26062466] |
| 25. Yu-Jia Nong, Qian-Yuan Wu, Yuan-Chu Qin, Zi-Bo Jing, Er-Dong Wang, Qing Bai, Wen-Long Wang. (2025) Enhanced Photolysis of Sulfite by Far-UVC (222 nm) and Efficient Photoreductive Degradation and Dehalogenation of Halogenated Organic Pollutants. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:40761014] [10.1021/acs.est.5c04240] |
| 26. Wei Wang, Qirui Wu, Hanzhi Wang, Mingxiang Qv, Dian Dai, Xiaoman He, Ivan P. Pozdnyakov, Li-Zhi Huang, Liandong Zhu. (2025) UV254 triggers chloroacetic acids degradation to generate degrading products for Chlorella sorokiniana growth: mechanism and performance evaluation. JOURNAL OF HAZARDOUS MATERIALS, [PMID:40834536] [10.1016/j.jhazmat.2025.139575] |
| 27. Xiaoqin Li, Yuqi Su, Ronghai Bai, Qibin Li. (2025) Effect of Chloride Ions on the Degradation of Phenol and the Formation of Chlorinated Byproducts in BDD and RuO2-IrO2/Ti Anode Systems. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2025.119089] |
| 28. Ziyuan Huang, Liangfeng Huang, Yanjuan Huang, Yuanfeng He, Xiaoqi Sun, Xiang Fu, Xiaoyu Xu, Gaofei Wei, Dawei Chen, Chunshun Zhao. (2017) Phthalocyanine-based coordination polymer nanoparticles for enhanced photodynamic therapy. Nanoscale, 9 (41): (15883-15894). [PMID:28994841] [10.1039/C7NR05402E] |
| 29. Shengcun Ma, Xiaoqi Guo, Baiyang Chen. (2016) Toward better understanding of chloral hydrate stability in water: Kinetics, pathways, and influencing factors. CHEMOSPHERE, [PMID:27206269] [10.1016/j.chemosphere.2016.05.018] |
| 30. Liu Jun-Ling, Zhang Xiao-Pan, Peng Chen-Wei, Luo Hai-Yuan, Liu Ai-Lin. (2025) Effect of haloacetic acid water disinfection byproducts on intestinal barrier function in nematode Caenorhabditis elegans. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, [PMID:40378183] [10.1093/etojnl/vgaf129] |
| 31. Xingxing Huang, Xiaojiang Huang, Muyu Feng, Haocheng Yang, Xuan Wang, Zhiqiang Zhang, Jinsuo Lu. (2025) Electrochemically assisted UV-enhanced boiling of drinking water to reduce human exposure to disinfection byproducts. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.164601] |
| 32. Wanyi Zhao, Haoran Chen, Man Zhang, Zhongbing Huang, Changsheng Zhao. (2025) A Heparin-Mimic Macromolecule Promoted Endothelial Cell Adhesion. MACROMOLECULAR BIOSCIENCE, [PMID:40537461] [10.1002/mabi.202500117] |
| 33. Jian Guan, Mengsen Niu, Zhangming Wang, Wujian Zhang, Zongjian Liu, Aiming Chen, Shengjie Xia, Panpan Zhang, Haodong Tang. (2026) Synthesis of ultrahigh molecular weight poly(vinylidene fluoride) via emulsion polymerization initiated by the combination of silver nanoparticles with trichloroacetic acid. POLYMER, [PMID:] [10.1016/j.polymer.2026.129607] |
| 34. Baoquan Liu, Lianchong Shao, Jiayun Yu, Feipeng Huang, Chengpu Chu, Shaoping Tong, Laiquan Li, Huan Wu, Yinghua Xu, Bin Liu. (2026) Electrochemical hydrogenation of halogenated disinfection byproducts in drinking water purification. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2026.137108] |
| 35. Fuyuan Tan, Jie Lyu, Guofeng Qu, Wenliang Li, Haiyue Peng, Yiwei Liu, Jiali Liao, Yuanyou Yang, Shuqiong Peng, Ning Liu, Feize Li. (2026) The Construction of a Multifunctional Nanoscale Porous Coordination Network-222 Nanodrug for Imaging-Guided Chemotherapy-Photodynamic Therapy. ACS Applied Bio Materials, [PMID:41618921] [10.1021/acsabm.5c02422] |
