≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Difluoromethyl triflate (HCF2OTf) is an easy to handle, air-stable and non-ozone-depleting liquid reagent for difluoromethylation. It can be prepared by reacting trifluoromethyltrimethylsilane (TMSCF3) and triflic acid in the presence of titanium tetrachloride (TiCl4)
| Canonical Smiles | C(OS(=O)(=O)C(F)(F)F)(F)F |
|---|---|
| IUPAC Name | difluoromethyl trifluoromethanesulfonate |
| InChIKey | DAANAKGWBDWGBQ-UHFFFAOYSA-N |
| INCHI | 1S/C2HF5O3S/c3-1(4)10-11(8,9)2(5,6)7/h1H |
| Isomeric SMILES | C(OS(=O)(=O)C(F)(F)F)(F)F |
| WGK Germany | 3 |
| Molecular Weight | 200.08 |
| Reaxy-Rn | 1870187 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1870187&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Organic sulfonic acids and derivatives |
| Subclass | Organosulfonic acids and derivatives |
| Intermediate Tree Nodes | Alkanesulfonic acids and derivatives - Alkanesulfonic acids |
| Direct Parent | Trifluoromethanesulfonates |
| Alternative Parents | Sulfonic acid esters Organosulfonic acid esters Sulfonyls Methanesulfonates Trihalomethanes Organooxygen compounds Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Trifluoromethanesulfonate - Sulfonic acid ester - Organosulfonic acid ester - Methanesulfonate - Sulfonyl - Trihalomethane - Alkyl fluoride - Hydrocarbon derivative - Halomethane - Organic oxide - Organosulfur compound - Organooxygen compound - Organofluoride - Organohalogen compound - Organic oxygen compound - Alkyl halide - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as trifluoromethanesulfonates. These are alkanesulfonic acids, that contain a sulfonate group that is substituted with a trifluoromethyl group. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 E2216006 | Certificate of Analysis | Oct 29, 2025 | D168172 |
| E2216103 | Certificate of Analysis | Oct 29, 2025 | D168172 |
| E2216110 | Certificate of Analysis | Oct 29, 2025 | D168172 |
| E2216011 | Certificate of Analysis | Feb 20, 2024 | D168172 |
| G2110187 | Certificate of Analysis | Apr 18, 2023 | D168172 |
| G2110186 | Certificate of Analysis | Apr 18, 2023 | D168172 |
| Sensitivity | Air and moisture sensitive |
|---|---|
| Flash Point(°F) | 134.6 °F |
| Flash Point(°C) | 57 °C |
| Molecular Weight | 200.090 g/mol |
| XLogP3 | 1.800 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 2 |
| Exact Mass | 199.957 Da |
| Monoisotopic Mass | 199.957 Da |
| Topological Polar Surface Area | 51.800 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 209.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
