Dimethyl malonate - Moligand™, 10 mM in DMSO , CAS No.108-59-8

CAS: 108-59-8 Cat. No.: D1501044 Molecular Weight: 132.11 Beilstein Registry Number: 774261 EC Number: 203-597-8
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
D1501044-1ml
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$45.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase ( SDH ). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis.

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Names and Identifiers
Isomeric SMILES COC(=O)CC(=O)OC
WGK Germany 1
RTECS OO0950000
Molecular Weight 132.11
Beilstein 774261
Reaxy-Rn 774261
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=774261&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Refractive Index1.4149
Flash Point(°F)185 °F
Flash Point(°C)90℃
Boil Point(°C)181.4°C
Melt Point(°C)-62°C
Documents & Articles
Citations of This Product
References
1. Yongliang Ding, Jiangjun Zhou, Lieshun Cai, Zhongkai Wang, Feng Jiang.  (2023)  Humidity-sensitive and fluorescent bio-based polyhydroxylamides toward sustainable adhesives.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2023.117423]
2. Zhang Yuanwen, Zheng Yueming, Wu Qingqing, Tian Fuyun, Ma Chuanjun, Xu Haiyan, Zhan Li, Gao Zhaobing, Zhao Guilong, Ti Huihui.  (2022)  Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel α2δ ligands for the treatment of chronic neuropathic pain.  MEDICINAL CHEMISTRY RESEARCH,  32  (2): (288-313).  [PMID:] [10.1007/s00044-022-03006-6]
3. Yuqing Shen, Chaoping Yuan, Xianyi Zhu, Qin Chen, Shenjun Lu, Haibo Xie.  (2021)  Engineering cellulose into water soluble poly(protic ionic liquid) electrolytes in the DBU/CO2/DMSO solvent system as an organocatalyst for the Knoevenagel condensation reaction.  GREEN CHEMISTRY,  23  (24): (9922-9934).  [PMID:] [10.1039/D1GC03148A]
4. Shuai Sun, Yijiao Xue, Xiaodong Xu, Liping Ding, Zhen Jiang, Linghui Meng, Pingan Song, Yongping Bai.  (2021)  Highly Stretchable, Ultratough, and Strong Polyesters with Improved Postcrystallization Optical Property Enabled by Dynamic Multiple Hydrogen Bonds.  MACROMOLECULES,      [PMID:] [10.1021/acs.macromol.0c02628]
5. Jie Yao, Yan Wang, Suleiman Sabo Bello, Guangwen Xu, Lei Shi.  (2020)  Regulation of Brønsted acid sites in H-MOR for selective methyl methoxyacetate synthesis.  APPLIED ORGANOMETALLIC CHEMISTRY,  34  (11): (e5925).  [PMID:] [10.1002/aoc.5925]
6. Fei Xia, Zhongtian Du, Junxia Liu, Yangyang Ma, Jie Xu.  (2016)  Catalytic oxidative C–C bond cleavage route of levulinic acid and methyl levulinate.  RSC Advances,  (76): (72744-72749).  [PMID:] [10.1039/C6RA16149A]
7. Abbas Tanver, Mu-Hua Huang, Yunjun Luo, Syed Khalid, Tariq Hussain.  (2015)  Energetic interpenetrating polymer network based on orthogonal azido–alkyne click and polyurethane for potential solid propellant.  RSC Advances,  (79): (64478-64485).  [PMID:] [10.1039/C5RA10467J]
8. Xie Tianyu, Hu Wenbo, You Lin, Wang Xin.  (2024)  Design, synthesis and biological evaluation of thienopyridine derivatives as c-Met kinase inhibitors.  MOLECULAR DIVERSITY,      [PMID:39356364] [10.1007/s11030-024-10998-3]
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