DL-Glutamic acid monohydrate - for cell culture, ≥98% , CAS No.19285-83-7

CAS: 19285-83-7 Cat. No.: G111548 Molecular Weight: 165.14

GRADE & PURITY for Cell culture, ≥98%

Synonyms

SCHEMBL910049 | OZDAOHVKBFBBMZ-UHFFFAOYSA-N | AKOS022174795 | MFCD00150703 | AMY16018 | 2-azanylpentanedioic acid hydrate | HMS1571C03 | DTXCID1029095 | DL-GlutamicAcidMonohydrate | NCGC00260356-01 | FT-0625463 | 2-aminopentanedioic acid;hydrate | (+/-)-2

Storage

Room temperature

Shipped In

Normal

Overview

DL-Glutamic acid monohydrate is an excitatory amino acid neurotransmitter which acts as an agonist at kainate, NMDA, AMPA and metabotropic glutamatergic receptors. L-Glutamic acid is a proteinogenic amino acid incorporated into proteins as directed by the genetic code. This product is a mixture of D and L isomers of glutamic acid.
A glutamatergic receptor agonist

Specifications

Synonyms

SCHEMBL910049 | OZDAOHVKBFBBMZ-UHFFFAOYSA-N | AKOS022174795 | MFCD00150703 | AMY16018 | 2-azanylpentanedioic acid hydrate | HMS1571C03 | DTXCID1029095 | DL-GlutamicAcidMonohydrate | NCGC00260356-01 | FT-0625463 | 2-aminopentanedioic acid;hydrate | (+/-)-2

Specifications & Purity

for cell culture, ≥98%

Biochemical and Physiological Mechanisms

Excitatory amino acid neurotransmitter that is an agonist at kainate, NMDA, AMPA, and metabotropic glutamatergic receptors.

Storage

Room temperature

Shipped In

Normal

Grade

for Cell culture

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504768400
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504768400
• Canonical Smiles: C(CC(=O)O)C(C(=O)O)N.O
• IUPAC Name: 2-aminopentanedioic acid;hydrate
• InChIKey: OZDAOHVKBFBBMZ-UHFFFAOYSA-N
• INCHI: 1S/C5H9NO4.H2O/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);1H2
• Isomeric SMILES: C(CC(=O)O)C(C(=O)O)N.O
• Molecular Weight: 165.14
• Reaxy-Rn: 4155097
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4155097&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Glutamic acid and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Glutamic acid and derivatives
• Alternative Parents: Alpha amino acids Amino fatty acids Dicarboxylic acids and derivatives Amino acids Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Glutamic acid or derivatives - Alpha-amino acid - Amino fatty acid - Dicarboxylic acid or derivatives - Fatty acid - Fatty acyl - Amino acid - Carboxylic acid - Organic oxide - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Amine - Organic nitrogen compound - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as glutamic acid and derivatives. These are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: 1 M HCl: 100 mg/mL, clear, colorless
• Sensitivity: Moisture sensitive.
• Melt Point(°C): 197-199°C
• Molecular Weight: 165.140 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 165.064 Da
• Monoisotopic Mass: 165.064 Da
• Topological Polar Surface Area: 102.000 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 145.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Yan Tang, Xiaohan Xia, Zhenqi Zhu, Xun Zhang, Bin Yang.  (2024)  Terahertz spectroscopic study of the dehydration process and hydrogen bonding network of DL-glutamic acid and its monohydrate.  JOURNAL OF MOLECULAR STRUCTURE,      [PMID:] [10.1016/j.molstruc.2024.138610]

2. Mei Lin, Wei Bingjie, Liu Chunyan, Zhao Mengting, Cui Tian, Wei Xiangyang.  (2025)  Polyvinylpyrrolidone-stabilized ultra-small Fe3O4 nanoparticles-functionalized graphene oxide with synergistically enhanced peroxidase-like activity for glutathione colorimetric determination in rat serum.  MICROCHIMICA ACTA,  192  (4): (1-11).  [PMID:40131482] [10.1007/s00604-025-07044-w]