DPO-1 - Moligand™, ≥98% , Channel blocker of K v1.5, CAS No.43077-30-1, Channel blocker of K v1.5

CAS: 43077-30-1 Cat. No.: D287466 Molecular Weight: 340.44
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
p-(2-Hydroxy-1-naphthylazo)benzenesulfonic acid sodium salt | SDCCGSBI-0633727.P001 | LP00543 | UNII-H9LQP293GK | Q27165442 | DPO 1 | DPO1 | DPO-1 | HMS3413F13 | Neomenthyldiphenylphosphine oxide | DTXSID10616838 | W-105388 | BPCNGVCAHAIZEE-COPCDDAFSA-N |
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
D287466-5mg
2

$95.90

$143.90
Save $48.00 (33.36%)
10mg
D287466-10mg
2

$171.90

$257.90
Save $86.00 (33.35%)
25mg
D287466-25mg
2

$395.90

$593.90
Save $198.00 (33.34%)
50mg
D287466-50mg
2

$573.90

$860.90
Save $287.00 (33.34%)
100mg
D287466-100mg
2

$821.90

$1,232.90
Save $411.00 (33.34%)
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
p-(2-Hydroxy-1-naphthylazo)benzenesulfonic acid sodium salt | SDCCGSBI-0633727.P001 | LP00543 | UNII-H9LQP293GK | Q27165442 | DPO 1 | DPO1 | DPO-1 | HMS3413F13 | Neomenthyldiphenylphosphine oxide | DTXSID10616838 | W-105388 | BPCNGVCAHAIZEE-COPCDDAFSA-N |
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
DPO-1 is an inhibitor of human Kv1.5 potassium channel; representative blocker of a novel pharmacophore. The Kv1.5 potassium channel, which underlies the ultrarapid delayed rectifier current, IKur, is reported to be enriched in human atrium versus ventric
Storage
Protected from light, Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
CHANNEL BLOCKER
Mechanism of action
Channel blocker of K v1.5
Purity
≥98%
Names and Identifiers
Pubchem Sid504769020
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504769020
Canonical SmilesCC1CCC(C(C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C(C)C
IUPAC Name[[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene
InChIKeyBPCNGVCAHAIZEE-COPCDDAFSA-N
INCHI1S/C22H29OP/c1-17(2)21-15-14-18(3)16-22(21)24(23,19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-13,17-18,21-22H,14-16H2,1-3H3/t18-,21+,22+/m1/s1
Isomeric SMILES C[C@@H]1CC[C@H]([C@H](C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C(C)C
Molecular Weight 340.44
Reaxy-Rn 10267089
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10267089&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClassPrenol lipids
SubclassMonoterpenoids
Intermediate Tree Nodes Not available
Direct ParentAromatic monoterpenoids
Alternative Parents Monocyclic monoterpenoids  Menthane monoterpenoids  Phenylphosphines and derivatives  Organopnictogen compounds  Organophosphorus compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents P-menthane monoterpenoid - Monocyclic monoterpenoid - Aromatic monoterpenoid - Phenylphosphine - Benzenoid - Monocyclic benzene moiety - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organophosphorus compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as aromatic monoterpenoids. These are monoterpenoids containing at least one aromatic ring.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
KCNA5 Tclin Potassium voltage-gated channel subfamily A member 5 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNA5 Tclin Voltage-gated potassium channel subunit Kv1.5 (1353 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ARSA Tbio Cerebroside-sulfatase (655 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U2OS (164939 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK-293T (167025 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
K2212600Certificate of AnalysisAug 18, 2025 D287466
K2212593Certificate of AnalysisAug 18, 2025 D287466
K2212544Certificate of AnalysisAug 18, 2025 D287466
K2212543Certificate of AnalysisAug 18, 2025 D287466
K2212542Certificate of AnalysisAug 18, 2025 D287466
C2507179Certificate of AnalysisJul 04, 2022 D287466
Chemical and Physical Properties
SolubilitySolvent:ethanol, Max Conc. mg/mL: 34.04, Max Conc. mM: 100
Sensitivitylight sensitive
Molecular Weight340.400 g/mol
XLogP36.000
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count4
Exact Mass340.196 Da
Monoisotopic Mass340.196 Da
Topological Polar Surface Area17.100 Ų
Heavy Atom Count24
Formal Charge0
Complexity409.000
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

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