DSPE-PEG-2K-CH2COOH , CAS No.474922-20-8

CAS: 474922-20-8 Cat. No.: D596707
AVAILABLE TO ORDER
Synonyms
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000]
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
D596707-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$72.90
25mg
D596707-25mg
1
$279.90
100mg
D596707-100mg
1
$756.90
250mg
D596707-250mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,218.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

DSPE-PEG-2K-CH2COOH is a PEG derivative containing DSPE and biotin end groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The CH2COOH group can be reacted with primary amines in the presence of activators such as EDC and DCC to form stable amide bonds.

Specifications

Synonyms
1, 2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000]
Storage
Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Canonical SmilesCCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)OCCOCC(=O)O)OC(=O)CCCCCCCCCCCCCCCCC.N
IUPAC Nameazane;2-[2-[2-[2,3-di(octadecanoyloxy)propoxy-hydroxyphosphoryl]oxyethylcarbamoyloxy]ethoxy]acetic acid
InChIKeyMFOLYTNLQCGGBD-UHFFFAOYSA-N
INCHI1S/C46H88NO13P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-44(50)57-39-42(40-59-61(53,54)58-36-35-47-46(52)56-38-37-55-41-43(48)49)60-45(51)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h42H,3-41H2,1-2H3,(H,47,52)(H,48,49)(H,53,54);1H3

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
E2530348Certificate of AnalysisMay 24, 2025 D596707
E2530355Certificate of AnalysisMay 24, 2025 D596707
E2530356Certificate of AnalysisMay 24, 2025 D596707
E2530357Certificate of AnalysisMay 24, 2025 D596707
E2530358Certificate of AnalysisMay 24, 2025 D596707
Citations of This Product
References
1. Xiaojuan Hu, Xingwen Cheng, Liqiang Shao, Lan Yang, Gongning Chen, Zhangwei Yan, Mengdie Yu, Yehui Kang, Xiaozhou Mou, Xianghong Yang, Yu Cai.  (2025)  NIR-II Light-Controlled Photosynthetic Activation via an Upconversion Nanoplatform for Targeted Bioenergetic Therapy in Acute Kidney Injury.  JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:40934095] [10.1021/acs.jmedchem.5c02109]
2. Yehui Kang, Yahui Zhang, Weijiao Fan, Liya Yu, Mengdie Yu, Yuejia Ding, Yu Cai, Aihong Jiao, Jiajie Xu.  (2026)  NIR-II conjugated polymer/emodin nanoplatform for mild photothermal therapy/pyroptosis of head and neck squamous cell carcinoma.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:41483565] [10.1016/j.jcis.2025.139800]
Solution Calculators
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