Erythrosin B - ≥85% , CAS No.16423-68-0

CAS: 16423-68-0 Cat. No.: E108729 Molecular Weight: 879.88 Beilstein Registry Number: 1443945 EC Number: 240-474-8 PubChem CID: 12961638
AVAILABLE TO ORDER
GRADE & PURITY ≥85%
Synonyms
Erythrosin extra bluish, certified by the Biological Stain Commission | 2',4',5',7'-Tetraiodofluorescein, disodium salt | Benzenesulfonic acid, 2,2'-(1,2-ethenediyl)bis(5-((4-(methylamino)-6-(phenylamino)-1,3,5-triazin-2-yl)amino)-, sodium salt (1:?) | C.
Storage
Protected from light,Desiccated,Room temperature
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Normal
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E108729-1g
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E108729-5g
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E108729-25g
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100g
E108729-100g
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500g
E108729-500g
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Why this grade

≥85% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Desiccated,Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 22 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Erythrosin extra bluish, certified by the Biological Stain Commission | 2', 4', 5', 7'-Tetraiodofluorescein, disodium salt | Benzenesulfonic acid, 2, 2'-(1, 2-ethenediyl)bis(5-((4-(methylamino)-6-(phenylamino)-1, 3, 5-triazin-2-yl)amino)-, sodium salt (1:?) | C.
Specifications & Purity
≥85%
Storage
Protected from light, Desiccated, Room temperature
Shipped In
Normal
Purity
≥85%
Names and Identifiers
Pubchem Sid488198303
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488198303
Canonical SmilesC1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C(=C4OC5=C(C(=C(C=C35)I)[O-])I)I)[O-])I.[Na+].[Na+]
IUPAC Namedisodium;2',4',5',7'-tetraiodo-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate
InChIKeyRAGZEDHHTPQLAI-UHFFFAOYSA-L
INCHI1S/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2
Isomeric SMILES C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C(=C4OC5=C(C(=C(C=C35)I)[O-])I)I)[O-])I.[Na+].[Na+]
WGK Germany 3
RTECS LM5950000
PubChem CID 12961638
Molecular Weight 879.88
Beilstein 1443945
Reaxy-Rn 3583865

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassBenzopyrans
Subclass1-benzopyrans
Intermediate Tree Nodes Dibenzopyrans
Direct ParentXanthenes
Alternative Parents Diarylethers  Phthalides  Benzofuranones  Isobenzofurans  Phenoxides  Aryl iodides  Carboxylic acid esters  Lactones  Oxacyclic compounds  Organic metal halides  Monocarboxylic acids and derivatives  Hydrocarbon derivatives  Organic oxides  Organic sodium salts  Organic zwitterions  Organoiodides  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Xanthene - Diaryl ether - Benzofuranone - Isobenzofuranone - Phthalide - Isocoumaran - Isobenzofuran - Phenoxide - Aryl halide - Aryl iodide - Benzenoid - Carboxylic acid ester - Lactone - Organic metal halide - Carboxylic acid derivative - Oxacycle - Ether - Organic alkali metal salt - Monocarboxylic acid or derivatives - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Organohalogen compound - Organoiodide - Organooxygen compound - Organic sodium salt - Organic salt - Organic zwitterion - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
HSPD1 Tbio HSP60/HSP10 (366 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TST Tchem Thiosulfate sulfurtransferase (144 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
groL GroEL/GroES (1042 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

20 results found

Lot NumberCertificate TypeDateItem
I2412111Certificate of AnalysisJun 11, 2026 E108729
A1523070Certificate of AnalysisFeb 05, 2026 E108729
I2001021Certificate of AnalysisDec 22, 2025 E108729
I2001020Certificate of AnalysisDec 22, 2025 E108729
K2120270Certificate of AnalysisAug 15, 2023 E108729
K2119323Certificate of AnalysisAug 15, 2023 E108729
J2123553Certificate of AnalysisJul 11, 2023 E108729
J2123552Certificate of AnalysisJul 11, 2023 E108729
I1903025Certificate of AnalysisMar 10, 2023 E108729
F2102261Certificate of AnalysisMar 10, 2023 E108729
B2315545Certificate of AnalysisMar 02, 2023 E108729
B2321177Certificate of AnalysisFeb 27, 2023 E108729
B2321174Certificate of AnalysisFeb 27, 2023 E108729
B2321148Certificate of AnalysisFeb 27, 2023 E108729
B2321124Certificate of AnalysisFeb 27, 2023 E108729
B2321101Certificate of AnalysisFeb 27, 2023 E108729
B2321144Certificate of AnalysisFeb 27, 2023 E108729
B2321179Certificate of AnalysisFeb 24, 2023 E108729
B2321100Certificate of AnalysisFeb 24, 2023 E108729
B2318490Certificate of AnalysisFeb 23, 2023 E108729

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Chemical and Physical Properties
SolubilitySoluble in water (100 mg/ml at 20 °C), alcohol, and methanol.
SensitivityMoisture sensitive.
Molecular Weight879.900 g/mol
XLogP3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass879.619 Da
Monoisotopic Mass879.619 Da
Topological Polar Surface Area81.700 Ų
Heavy Atom Count31
Formal Charge0
Complexity645.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count3
Citations of This Product
References
1. Xie Yifan, Feng Shuo, Deng Linxiao, Cai Aoran, Gan Liyu, Jiang Zifan, Yang Peng, Ye Guilin, Liu Zaiqing, Wen Li, Zhu Qing, Zhang Wanjun, Zhang Zhanpeng, Li Jiahe, Feng Zeyu, Zhang Chutian, Du Wenjie, Xu Lixin, Jiang Jun, Chen Xin, Zou Gang.  (2023)  Inverse design of chiral functional films by a robotic AI-guided system.  Nature Communications,  14  (1): (1-13).  [PMID:37794036] [10.1038/s41467-023-41951-x]
2. Yuanyuan Li, Haowen Li, Tiancong Wang, Gang Liu, Gang Wang, Miaomiao Liu, Li Pan, Juan He, Kai Li.  (2023)  Surface-molecularly imprinted ratiometric fluorescence sensor for fast, sensitive and selective determination of rhodamine 6G.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2023.111602]
3. Mengqi Cui, Yuting Li, Na Li, Xiujuan Hao, YangYang Zhang, Qikun Rong, Guofu Zhou, Li Nian.  (2023)  Combining ZnO and Organosilica Nanodots as a Thick Cathode Interlayer for Highly Efficient and Stable Inverted Polymer Solar Cells.  ACS Applied Energy Materials,      [PMID:] [10.1021/acsaem.3c00068]
4. Shuangshou Wang, Wenzhi Li, Zhihong Yuan, Qiwen Jin, Zongpeng Ding, Xiaomeng Liu, Mingfu Ye, Jing Gu, Tingxuan Yan, Hongmei Chen, Yang Chen.  (2022)  Semiquantitative naked-eye detection of synthetic food colorants using highly-branched pipette tip as an all-in-one device.  ANALYTICA CHIMICA ACTA,      [PMID:35589223] [10.1016/j.aca.2022.339901]
5. Xuqian Wang, Yuanyuan Peng, Tonghui Xie, Yongkui Zhang, Yabo Wang, Huan Yang.  (2022)  Photocatalytic removal of sulfamethoxazole using yeast biomass-derived NixP/biocarbon composites in the presence of dye sensitizer.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2022.107426]
6. Longming Jin, Lijie Hu, Songmiao Liang, Zhiliang Wang, Guoyang Xu, Xingsheng Yang.  (2022)  A novel organic solvent nanofiltration (OSN) membrane fabricated by Poly(m-phenylene isophthalamide) (PMIA) under large-scale and continuous process.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2022.120259]
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10. Qing Han, Ying Sun, Kangwei Shen, Yan Yan, Xuejun Kang.  (2021)  Rapid determination of seven synthetic dyes in casual snacks based on packed-fibers solid-phase extraction coupled with HPLC-DAD.  FOOD CHEMISTRY,      [PMID:33465694] [10.1016/j.foodchem.2021.129026]
11. Shengrui Zhang, Yang Yu, Shujue Xu, Jun Liu, Mo Liu, He Su, Yajiao Hao, Minjie Li, Sean Xiao-An Zhang.  (2020)  A Study on Au(I)-thiolate Nanosheets as Water-dispersible UV Absorbents.  ChemNanoMat,  (3): (270-276).  [PMID:] [10.1002/cnma.202000618]
12. Narmadha Manoranjan, Feng Zhang, Zhenyi Wang, Yanping Dong, Wangxi Fang, Yatao Zhang, Yuzhang Zhu, Jian Jin.  (2020)  A Single-Walled Carbon Nanotube/Covalent Organic Framework Nanocomposite Ultrathin Membrane with High Organic Solvent Resistance for Molecule Separation.  ACS Applied Materials & Interfaces,      [PMID:33169985] [10.1021/acsami.0c14825]
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14. Shiyu Li, Zhongying Zhang, Jingdong Peng, Xiang Wang, Dengying Long, Hong Xian, Ranxi Ni, Huanjun Peng, Jun Chen.  (2019)  High-performance liquid chromatography associated with resonance Rayleigh scattering spectral study of the interactions of palladium(II)–antimigraine chelates with Erythrosin B and their analytical applications.  NEW JOURNAL OF CHEMISTRY,  44  (7): (3078-3086).  [PMID:] [10.1039/C9NJ02390A]
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19. Piyong Zhang, Ting Song, Tingting Wang, Heping Zeng.  (2017)  Enhancement of hydrogen production of a Cu–TiO2 nanocomposite photocatalyst combined with broad spectrum absorption sensitizer Erythrosin B.  RSC Advances,  (29): (17873-17881).  [PMID:] [10.1039/C6RA27686E]
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