Ethyl maltol - 10mM in DMSO , CAS No.4940-11-8

CAS: 4940-11-8 Cat. No.: E424264 Molecular Weight: 140.14 EC Number: 225-582-5

GRADE & PURITY 10mM in DMSO

Synonyms

ETHYL MALTOL [II] | ETHYL MALTOL [FCC] | NCGC00254704-01 | 2-Ethyl-3-hydroxy-4H-pyran-4-one | AS-13959 | BP-12441 | Q-201087 | 3-Hydroxy-2-ethyl-.gamma.-pyrone | Ethyl Hydroxypyrone | STL559005 | 4H-PYRAN-4-ONE, 2-ETHYL-3-HYDROXY- | ETHYL MALTOL [MI] | AK

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications

Synonyms

ETHYL MALTOL [II] | ETHYL MALTOL [FCC] | NCGC00254704-01 | 2-Ethyl-3-hydroxy-4H-pyran-4-one | AS-13959 | BP-12441 | Q-201087 | 3-Hydroxy-2-ethyl-.gamma.-pyrone | Ethyl Hydroxypyrone | STL559005 | 4H-PYRAN-4-ONE, 2-ETHYL-3-HYDROXY- | ETHYL MALTOL [MI] | AK

Specifications & Purity

10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: CCC1=C(C(=O)C=CO1)O
• IUPAC Name: 2-ethyl-3-hydroxypyran-4-one
• InChIKey: YIKYNHJUKRTCJL-UHFFFAOYSA-N
• INCHI: 1S/C7H8O3/c1-2-6-7(9)5(8)3-4-10-6/h3-4,9H,2H2,1H3
• Isomeric SMILES: CCC1=C(C(=O)C=CO1)O
• WGK Germany: 3
• RTECS: UQ0840000
• Molecular Weight: 140.14
• Reaxy-Rn: 1618110
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1618110&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Pyrans
      • Subclass Pyranones and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Pyrans
• Subclass: Pyranones and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyranones and derivatives
• Alternative Parents: Heteroaromatic compounds Cyclic ketones Oxacyclic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Pyranone - Heteroaromatic compound - Cyclic ketone - Oxacycle - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as pyranones and derivatives. These are compounds containing a pyran ring which bears a ketone.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

Discover Target: ALOX5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TYR Tclin Tyrosinase (717 Activities)

Discover Target: TYR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)

Discover Target: MMP3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP8 Tchem Matrix metalloproteinase 8 (1942 Activities)

Discover Target: MMP8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)

Discover Target: MMP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Nos2 Nitric oxide synthase, inducible (3573 Activities)

Discover Target: Nos2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp2 Matrix metalloproteinase-2 (12 Activities)

Discover Target: Mmp2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp9 Matrix metalloproteinase 9 (38 Activities)

Discover Target: Mmp9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Melt Point(°C): 92°C
• Molecular Weight: 140.140 g/mol
• XLogP3: 0.800
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 140.047 Da
• Monoisotopic Mass: 140.047 Da
• Topological Polar Surface Area: 46.500 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 213.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Zepeng Li, Yuxiang Wu, Zijing Li, Binger Yu, Xinyi Mao, Guoqing Shi.  (2023)  A lateral flow immunoassay method for the rapid detection of acetochlor and alachlor in vegetable oil by sensitivity enhancement by using dimethyl-β-cyclodextrin.  Analytical Methods,  15  (38): (5087-5094).  [PMID:37747357] [10.1039/D3AY01379K]

2. Mengyao Guo, Shu Yu, Shu Zhang, Juntao Wei, Wenran Gao, Weina Bao, Lei Shi, Hong Zhang, Deliang Xu.  (2022)  Nitrogen Migration and Conversion in Chars from Co-Pyrolysis of Lignocellulose Derived Pyrolysis Model Compounds and Urea-Formaldehyde Resin Adhesive.  Energies,  15  (19): (7221).  [PMID:] [10.3390/en15197221]

3. Di Chen, Bin Wang, Xin-Li Xu, Man-Yu Zhang, Xin-Miao Bu, Sen Yang, Yanbo Luo, Xia Xu.  (2022)  Kapok fiber-supported liquid extraction for convenient oil samples preparations: A feasibility and proof-of-concept study.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:36095972] [10.1016/j.chroma.2022.463480]

4. Li Minglei, Wang Dingzhong, Zhao Wuduo, Xi Hui, Xu Hengyi, Sun Shihao, Fu Yingjie, Zhang Shusheng, Mao Jian, Zhang Jianxun.  (2022)  Simultaneous determination of multiple flavorings in infant formula by direct analysis in real time-mass spectrometry.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2022.113586]

5. Xin Fu, Dongliang Zhu, Lan Huang, Xiangyang Yan, Shaomin Liu, Chenghui Wang.  (2019)  Superparamagnetic core-shell dummy template molecularly imprinted polymer for magnetic solid-phase extraction of food additives prior to the determination by HPLC.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2019.104169]

6. Xuerui Lou, Minglei Li, Weiwei Guo, Yingjie Fu, Hui Xi, Peng Li, Wuduo Zhao, Shihao Sun.  (2024)  Rapid Determination of Flavorings in e-Cigarette Liquid by Direct Analysis in Real Time (DART) Mass Spectrometry (MS) in the Quick Strip Mode.  ANALYTICAL LETTERS,      [PMID:] [10.1080/00032719.2024.2308054]

7. Yanru Qiu, Yudong Wang, Wenrou Su, Feifei Wang.  (2025)  Revealing the impact of processing technology on the aroma profile of Roasted coffee (Coffea Arabica) oil using Flavoromics strategy and chemometrics.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.118913]

8. Jinhao Zou, Xuping Wang, Jingrong Cheng, Xueming Liu, Yantian Tang, Anping Li, Daobang Tang.  (2026)  Elucidating key aroma compounds of braised squab and providing insights into their potential precursor.  FOOD CHEMISTRY,      [PMID:] [10.1016/j.foodchem.2026.149613]