Recombinant Human GGN Protein: FAQs & Key Facts

Recombinant Human GGN Protein is a research-grade recombinant protein derived from the human GGN (Gametogenetin) gene, produced for use in studies related to spermatogenesis, male reproductive biology, and protein interaction assays.

Product Name

Recombinant Human GGN Protein

SKU

rp372289

Gene

GGN (Gametogenetin)

Species

Human (Homo sapiens)

Application

Research use only — protein interaction, functional assays, reproductive biology studies

Storage

Refer to product datasheet; typically stored at -20°C or -80°C; avoid repeated freeze-thaw cycles

What Is GGN and Why Is It Studied?

GGN, or Gametogenetin, is a protein encoded by the GGN gene in humans. It is predominantly expressed in the testis and has been implicated in spermatogenesis and male fertility. GGN is known to interact with SPRY domain-containing proteins and has been studied in the context of male reproductive development and potential links to infertility. As a research tool, Recombinant Human GGN Protein enables scientists to investigate its molecular interactions, functional roles, and expression characteristics in vitro without reliance on endogenous tissue sources.

Common Questions About Product Specifications

What is the recommended storage condition? Recombinant Human GGN Protein should be stored according to the instructions on the product datasheet. In general, recombinant proteins of this type are stored at −20°C for short-term use or at −80°C for long-term storage. Repeated freeze-thaw cycles should be avoided to preserve activity and integrity.

What purity level can I expect? Purity specifications are provided on the product datasheet (SKU: rp372289). Researchers are advised to consult the current datasheet available on the Aladdin Scientific website or request it from the technical support team, as exact purity values are lot-dependent.

What expression system is used? The expression system for Recombinant Human GGN Protein should be confirmed by reviewing the product datasheet for SKU rp372289, as expression host details (e.g., E. coli, HEK293, insect cells) can vary by product and lot.

Reconstitution and Handling Guidelines

Proper reconstitution is critical for maintaining the biological activity of Recombinant Human GGN Protein. General best practices include:

• Centrifuge the vial briefly before opening to collect lyophilized material at the bottom.
• Reconstitute using sterile, deionized water or the buffer specified in the product datasheet.
• Allow the protein to dissolve gently; avoid vigorous vortexing.
• After reconstitution, aliquot into single-use volumes to minimize freeze-thaw cycles.
• Use the reconstituted protein within the timeframe specified on the datasheet.

For specific reconstitution volumes and buffer compositions, always refer to the product datasheet for SKU rp372289 or contact Aladdin Scientific technical support.

Research Applications of Recombinant Human GGN Protein

Recombinant Human GGN Protein is intended for research use only and is suitable for a range of in vitro applications, including:

• Protein–protein interaction studies: Investigating GGN binding partners, particularly proteins containing SPRY domains.
• Functional assays: Exploring the role of GGN in signaling pathways relevant to spermatogenesis.
• Western blot standards: Using purified recombinant protein as a positive control or molecular weight marker in immunoblotting experiments.
• ELISA development: Serving as a standard antigen for assay development and antibody validation.
• Structural and biochemical studies: Characterizing GGN protein conformation and activity.

Researchers studying male infertility, reproductive biology, or testicular function may find this reagent particularly useful.

Ordering, Quality, and Support

How do I order Recombinant Human GGN Protein? This product (SKU: rp372289) can be ordered directly through the Aladdin Scientific website or by contacting your regional Aladdin Scientific representative. Bulk quantities and custom formulations may be available upon request.

Is a Certificate of Analysis (CoA) available? Yes. A lot-specific CoA is available for each batch of Recombinant Human GGN Protein. Please provide the lot number when requesting a CoA from Aladdin Scientific customer support.

What quality controls are applied? Recombinant proteins from Aladdin Scientific undergo quality control testing prior to release. Specific QC methods and results are detailed in the product datasheet and CoA. For further technical questions, contact Aladdin Scientific technical support.

Frequently asked questions

What is Recombinant Human GGN Protein used for?

Recombinant Human GGN Protein (SKU: rp372289) is used for research purposes including protein–protein interaction studies, functional assays related to spermatogenesis, Western blot positive controls, ELISA antigen standards, and structural characterization. It is not intended for diagnostic or therapeutic use.

How should Recombinant Human GGN Protein be stored after reconstitution?

After reconstitution, the protein should be aliquoted into single-use volumes to avoid repeated freeze-thaw cycles, and stored at the temperature specified in the product datasheet (typically -20°C or -80°C). Always consult the current datasheet for SKU rp372289 for lot-specific storage guidance.

What expression system is used to produce this recombinant protein?

The expression system details for Recombinant Human GGN Protein (SKU: rp372289) are specified on the product datasheet. Common expression hosts for recombinant human proteins include E. coli, HEK293 cells, and insect cell systems; please consult the datasheet or contact Aladdin Scientific technical support for the specific host used for this product.

Is a Certificate of Analysis available for Recombinant Human GGN Protein?

Yes, a lot-specific Certificate of Analysis (CoA) is available for each batch of Recombinant Human GGN Protein. Contact Aladdin Scientific customer support with your lot number to request the relevant CoA.

Can this protein be used for in vivo or clinical applications?

No. Recombinant Human GGN Protein (SKU: rp372289) is labeled for research use only and is not suitable for in vivo, diagnostic, or therapeutic applications in humans or animals.

References

1. Kimura M et al. Gametogenetin (GGN) is expressed in the gonads and interacts with SPRY domain-containing proteins. (General background reference — specific publication details require verification.)
2. Aladdin Scientific Product Datasheet: Recombinant Human GGN Protein, SKU rp372289. Aladdin Scientific.

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.