Articles by tag "ActRIIA"

1. ActRIIA/ActRIIB in Weight Loss: Muscle Preservation and Adipose Regulation
   posted this at Oct 15, 2026

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   ActRIIA and ActRIIB are important receptors for TGF-β superfamily ligands such as Myostatin/GDF8 and Activin A. Through SMAD2/3 signaling, they restrict skeletal muscle growth and participate in adipose tissue metabolism. Blocking ActRIIA/ActRIIB can increase or preserve Lean Mass while ...