Articles by Topic "GSSG"

1. Glutathione Reductase: A Flavin-Dependent Reductive System Maintaining GSH/GSSG Homeostasis, with Assays and Applications
   posted this at Feb 25, 2026

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   Glutathione reductase (GR) is a canonical flavin-dependent oxidoreductase that catalyzes the reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as the electron donor, thereby maintaining the steady state of the intracellular GSH/GSSG redox-buffering system.
2. Glutathione (GSH) Quantification: Method Systems, Experimental Workflows, and Key Quality-Control Considerations
   posted this at Feb 11, 2026

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   Glutathione (GSH) is one of the most important low-molecular-weight thiols in cells. It participates in reactive oxygen species (ROS) detoxification, maintains protein thiols in a reduced state, drives the glutathione peroxidase/reductase cycle, and—together with oxidized glutathione ...