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FTO-IN-8 - ≥98% , CAS No.2640366-38-5
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase ( FTO ) (fat mass- and obesity-associated protein) inhibitor with the IC 50 value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity.
In Vitro
FTO-IN-8 (FTO-43) (0-50 μM, 24-72 h) inhibits the proliferation of cancer cells with no cytotoxicity to normal colonic cells. FTO-IN-8 (FTO-43) can increase m 6 A and m 6 A m levels and inhibits Wnt/PI3K-Akt signaling in gastric cancer AGS cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: AGS, SNU16, and KATOIII cell lines Concentration: 0-50 μM Incubation Time: 24, 48, 72 hours Result: Inhibited the growth of SNU16, KATOIII and AGS with the EC 50 values of 17.7 μM, 35.9 μM and 20.3 μM, respectively.
Form:Oil
Specifications
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase ( FTO ) (fat mass- and obesity-associated protein) inhibitor with the IC 50 value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥98%
Names and Identifiers
| Molecular Weight | 346.85 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMSO : ≥ 100 mg/mL (288.31 mM) |
|---|
Solution Calculators
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