Gcase activator 2 - ≥98% , CAS No.2759897-35-1

CAS: 2759897-35-1 Cat. No.: G647842 Molecular Weight: 364.44

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Gcase activator 2 (compound 14), a pyrrolo[2,3-b]pyrazine, is alos a β-Glucocerebrosidase ( GCase ) activator ( EC 50 =3.8 μM). Gcase activator 2 induces GCase dimerizatio (both K-type and V-type). And Gcase activator 2 has low metabolic clearance in human and mouse

In Vitro

Gcase activator 2 has low metabolic clearance in human and mouse with CL values of 10 and 12 μL/min/mg, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:β-Glucocerebrosidase

Specifications

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Gcase activator 2 (compound 14), a pyrrolo[2, 3-b]pyrazine, is alos a β-Glucocerebrosidase ( GCase ) activator ( EC 50 =3.8 μM). Gcase activator 2 induces GCase dimerizatio (both K-type and V-type). And Gcase activator 2 has low metabolic clearance in huma

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Molecular Weight: 364.44