[³H]pyrilamine - Moligand™ , Antagonist of H 1 receptor;Antagonist of H 4 receptor, CAS No.H614211, Antagonist of H 1 receptor;Antagonist of H 4 receptor

CAS: H614211 Cat. No.: H614211 PubChem CID: 656400

GRADE & PURITY Moligand™

Synonyms

[³H]mepyramine

Storage

Room temperature

Specifications

Synonyms

[³H]mepyramine

Specifications & Purity

Moligand™

Storage

Room temperature

Grade

Moligand™

Action Type

ANTAGONIST

Mechanism of action

Antagonist of H 1 receptor;Antagonist of H 4 receptor

Names and Identifiers

• Canonical Smiles: COc1ccc(cc1)CN(c1ccc(cn1)[3H])CCN(C)C
• IUPAC Name: N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(5-tritiopyridin-2-yl)ethane-1,2-diamine
• InChIKey: YECBIJXISLIIDS-XHHURNKPSA-N
• INCHI: 1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3/i5T
• Isomeric SMILES: [3H]C1=CC=C(N=C1)N(CCN(C)C)CC2=CC=C(C=C2)OC
• PubChem CID: 656400

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Benzylamines

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Benzylamines
• Intermediate Tree Nodes: Not available
• Direct Parent: 2-benzylaminopyridines
• Alternative Parents: Phenoxy compounds Methoxybenzenes Dialkylarylamines Anisoles Aminopyridines and derivatives Alkyl aryl ethers Imidolactams Heteroaromatic compounds Trialkylamines Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 2-benzylaminopyridine - Phenoxy compound - Anisole - Methoxybenzene - Dialkylarylamine - Phenol ether - Alkyl aryl ether - Aminopyridine - Imidolactam - Pyridine - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Ether - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Amine - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as 2-benzylaminopyridines. These are aromatic compounds containing pyridine ring substituted at the 2-position by a benzylamine group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

HRH4 Tchem Histamine H4 receptor (1 Activities)

Discover Target: HRH4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor (0 Activities)

Discover Target: HRH1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)