HG-10-102-01 - Moligand™, 10 mM in DMSO , CAS No.1351758-81-0

CAS: 1351758-81-0 Cat. No.: H1496348 Molecular Weight: 377.83

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

HG-10-102-01 is a highly potent, selective, and brain-penetrable LRRK2 inhibitor, with IC 50 values of 20.3 and 3.2 nM against wild-type LRRK2 and LRRK2 , respectively. HG-10-102-01 also inhibits MNK2 and MLK1 , with IC 50 values of 0.6 and 2.1 μM. HG-10-102-01 can be used for Parkinson's disease (PD) research .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Names and Identifiers

• Isomeric SMILES: CNC1=NC(=NC=C1Cl)NC2=C(C=C(C=C2)C(=O)N3CCOCC3)OC
• MeSH Entry Terms: (11C)HG-10-102-01;(4-((5-chloro-4-(methylamino)pyrimidin-2-yl)amino)-3-methoxyphenyl)(morpholino)methanone;HG-10-102-01
• Molecular Weight: 377.83
• Reaxy-Rn: 22057904
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22057904&ln=