≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 504750415 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504750415 |
| Canonical Smiles | C1=CC(=C(C=C1O)CC(=O)O)O |
| IUPAC Name | 2-(2,5-dihydroxyphenyl)acetic acid |
| InChIKey | IGMNYECMUMZDDF-UHFFFAOYSA-N |
| INCHI | 1S/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12) |
| Isomeric SMILES | C1=CC(=C(C=C1O)CC(=O)O)O |
| Molecular Weight | 168.15 |
| Beilstein | 10407 |
| Reaxy-Rn | 2692860 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2692860&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Phenylacetic acids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 2(hydroxyphenyl)acetic acids |
| Alternative Parents | Hydroquinones 1-hydroxy-2-unsubstituted benzenoids Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | 2(hydroxyphenyl)acetic acid - Hydroquinone - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as 2(hydroxyphenyl)acetic acids. These are phenylacetic acids that carry a hydroxyl group at the 2-position. |
| External Descriptors | hydroquinones - dihydroxyphenylacetic acid |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2216471 | Certificate of Analysis | Apr 07, 2026 | H157029 |
| L2505476 | Certificate of Analysis | Dec 13, 2025 | H157029 |
| L2505477 | Certificate of Analysis | Dec 12, 2025 | H157029 |
| K2524605 | Certificate of Analysis | Nov 29, 2025 | H157029 |
| K2524656 | Certificate of Analysis | Nov 25, 2025 | H157029 |
| C2527263 | Certificate of Analysis | Mar 31, 2025 | H157029 |
| I2418365 | Certificate of Analysis | Sep 25, 2024 | H157029 |
| I2418366 | Certificate of Analysis | Sep 25, 2024 | H157029 |
| I2308639 | Certificate of Analysis | Sep 16, 2023 | H157029 |
| I2308642 | Certificate of Analysis | Sep 16, 2023 | H157029 |
| I2308651 | Certificate of Analysis | Sep 16, 2023 | H157029 |
| I2308655 | Certificate of Analysis | Sep 16, 2023 | H157029 |
| E2311147 | Certificate of Analysis | Jul 21, 2022 | H157029 |
| G2216350 | Certificate of Analysis | Jul 21, 2022 | H157029 |
| Melt Point(°C) | 147 °C |
|---|---|
| Molecular Weight | 168.150 g/mol |
| XLogP3 | 0.500 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 168.042 Da |
| Monoisotopic Mass | 168.042 Da |
| Topological Polar Surface Area | 77.800 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 168.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Shiling Liu, Siying Qin, Tengfei Zhang, Heng Zhang, Junqi Zhu, Xiaoli Li, Yuanfu Li, Feng Zhao. (2025) Basing target enzyme study the enantioselective bioactivity action mechanism of flusulfinam, a novel HPPD inhibitor herbicide. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, [PMID:40082037] [10.1016/j.pestbp.2025.106346] |
| 2. Wendi Xuan, Yupei Hu, Sicong Li, Xiaozhen Zhou, Meng Chen, Chenyao Wu, Xiang Gao, Gaoyan Xu, Jine Zhao, Lili Xia, Wei Feng, Yu Chen. (2025) Biohybrid Bacteria as Living Nanofactories for Disrupting Diabetic Wound Pathological Cascade via Antimicrobial-Regenerative Coupling. Advanced Healthcare Materials, [PMID:41025751] [10.1002/adhm.202503107] |
| 3. Liu Xin, Xu Qing-qing, Zhang Yi-bo, Yuan Shi-yu, Huang Wen-li, Pi Ming-shan, Xiong Qi, Gui Yu-ran, Deng Shi-chao, Wan Ling, Xiao Yi-fan, Wang Xiao-chuan, Shu Xi-ji, Xia Yi-yuan. (2026) Homogentisic Acid Disrupts the Blood–Brain Barrier and Promotes Aβ Aggregation in Alzheimer’s Disease. Current Medical Science, [PMID:41642448] [10.1007/s11596-026-00165-0] |
| 4. Zhu Xiangyu, Lin Jiawen, Liang Shuli, Qiu Chenyi, Jiang Yuchen, Liu Hengrui, Zhu Kun, Wang Qi, Du Chenfeng, Li Yonghao, Mao Yuanhui, Zheng Huanbin, Liu Chengan, Zhao Yeyao, An Meirong, Wu Yifeng, Liu Jun, Zhang Xinying, Lin Ying. (2026) Biosynthesis of pyomelanin from methanol with engineered Komagataella phaffii and its characterizations. Nature Communications, [PMID:] [10.1038/s41467-026-70512-1] |
