Inclisiran sodium - ≥95% , CAS No.1639324-58-5

CAS: 1639324-58-5 Cat. No.: I651822 Molecular Weight: 17284.72

GRADE & PURITY ≥95%

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. Inclisiran can be used for hyperlipidemia and cardiovascular disease (CVD) research.

In Vitro

Inclisiran is a double-stranded small RNA molecule that works by blocking the transcription of proprotein convertase subtilisin kexin 9 (PCSK-9), leading to a reduction of PCSK-9 levels in the hepatocytes, resulting in an increased expression of low-density lipoprotein (LDL) receptors in the hepatocyte membrane and, as a consequence, it reduces the circulating levels of LDL cholesterol (LDL-C). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Specifications & Purity

≥95%

Biochemical and Physiological Mechanisms

Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9 . Inclisiran can be used for hyperlipidemia and cardiovascular disease (CVD) research.

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Canonical Smiles: [Inclisiran]
• Alternate CAS: 1639324-62-1
• Molecular Weight: 17284.72

Chemical and Physical Properties

• Solubility: H2O : 5 mg/mL (0.31 mM; Need ultrasonic)
• Sensitivity: Moisture sensitive