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J30-8 - Moligand™,≥99% , CAS No.2366255-71-0

CAS: 2366255-71-0 Cat. No.: J651095 Molecular Weight: 373.79 PubChem CID: 4078145
COA
J30-8 - ≥99% CAS No(2366255-71-0) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
Synonyms
(5Z)-2-(2-Chlorophenylimino)-5-(5-fluoro-2-oxoindolin-3-ylidene)thiazolidin-4-one | 2-((2-Chlorophenyl)imino)-5-((Z)-5-fluoro-2-oxoindolin-3-ylidene)thiazolidin-4-one
Storage
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
J651095-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$29.90
5mg
J651095-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
10mg
J651095-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$119.90
25mg
J651095-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$279.90
50mg
J651095-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$499.90
100mg
J651095-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$899.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
🧪

Why this grade

Moligand™,≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

J30-8 is a potent and isoform-selective inhibitor of c-Jun N-terminal kinase 3 (JNK3) with an IC50 of 40 nM, which 2500-fold isoform selectivity against JNK1α1 and JNK2α2. J30-8 exhibits neuroprotective activity in vitro and potential for the treatment of neurodegenerative diseases.

Specifications

Synonyms
(5Z)-2-(2-Chlorophenylimino)-5-(5-fluoro-2-oxoindolin-3-ylidene)thiazolidin-4-one | 2-((2-Chlorophenyl)imino)-5-((Z)-5-fluoro-2-oxoindolin-3-ylidene)thiazolidin-4-one
Specifications & Purity
Moligand™, ≥99%
Storage
Protected from light, Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Purity
≥99%
Names and Identifiers
Canonical SmilesC1=CC=C(C(=C1)NC2=NC(=C(S2)C3=C4C=C(C=CC4=NC3=O)F)O)Cl
IUPAC Name3-[2-(2-chloroanilino)-4-hydroxy-1,3-thiazol-5-yl]-5-fluoroindol-2-one
InChIKeyBDCJVPSBCYWSSS-UHFFFAOYSA-N
INCHI1S/C17H9ClFN3O2S/c18-10-3-1-2-4-12(10)21-17-22-16(24)14(25-17)13-9-7-8(19)5-6-11(9)20-15(13)23/h1-7,24H,(H,21,22)
Isomeric SMILES C1=CC=C(C(=C1)NC2=NC(=C(S2)C3=C4C=C(C=CC4=NC3=O)F)O)Cl
PubChem CID 4078145
Molecular Weight 373.79

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAPK9 Tchem c-Jun N-terminal kinase 2 (4655 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAPK10 Tchem c-Jun N-terminal kinase 3 (3396 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAPK8 Tchem c-Jun N-terminal kinase 1 (5038 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
YES1 Tclin Tyrosine-protein kinase YES (2781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilityDMSO : 6.67 mg/mL (17.84 mM; ultrasonic and warming and heat to 60°C)
SensitivityLight sensitive, Moisture sensitive
Molecular Weight373.800 g/mol
XLogP33.900
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass373.009 Da
Monoisotopic Mass373.009 Da
Topological Polar Surface Area103.000 Ų
Heavy Atom Count25
Formal Charge0
Complexity721.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →
Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

View related series

JNK (62) MAPK/ERK Pathway (553)
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