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· · COA & SDS available for every product · Same-day shipping on in-stock items JW 67 - ≥97%(HPLC) , CAS No.442644-28-2
Synonyms
BDBM50380615 | SMR000013289 | ChemDiv1_018326 | SR-01000537125 | JW67, >=98% (HPLC) | HMS2324F10 | trispiro[indole-3,2'-[1,3]dioxane-5',5''-[1,3]dioxane-2'',3'''-indole]-2,2'''(1H,1'''H)-dione | AKOS000550561 | MLS001385179 | HMS3429N11 | STK056247 | SR-0
Shipped In
Ice chest + Ice pads
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Why this grade ≥97%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
BDBM50380615 | SMR000013289 | ChemDiv1_018326 | SR-01000537125 | JW67, >=98% (HPLC) | HMS2324F10 | trispiro[indole-3, 2'-[1, 3]dioxane-5', 5''-[1, 3]dioxane-2'', 3'''-indole]-2, 2'''(1H, 1'''H)-dione | AKOS000550561 | MLS001385179 | HMS3429N11 | STK056247 | SR-0
Specifications & Purity
≥97%(HPLC)
Biochemical and Physiological Mechanisms
Inhibitor of canonical Wnt pathway signaling (IC50= 1.17μM); targets theβ-catenin destruction complex (GSK-3β/AXIN/APC) to induceβ-catenin degradation. Selective for the canonical Wnt pathway over the Sonic hedgehog (Shh) and NF-κB pathways. Blocks G1/S c
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Pubchem Sid 504759769 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504759769 Canonical Smiles C1C2(COC3(O1)C4=CC=CC=C4NC3=O)COC5(C6=CC=CC=C6NC5=O)OC2 InChIKey BTXRSHKJNDFHGA-UHFFFAOYSA-N INCHI 1S/C21H18N2O6/c24-17-20(13-5-1-3-7-15(13)22-17)26-9-19(10-27-20)11-28-21(29-12-19)14-6-2-4-8-16(14)23-18(21)25/h1-8H,9-12H2,(H,22,24)(H,23,25) Isomeric SMILES C1C2(COC3(O1)C4=CC=CC=C4NC3=O)COC5(C6=CC=CC=C6NC5=O)OC2 WGK Germany 3 Molecular Weight 394.38 Reaxy-Rn 25469110 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25469110&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Indoles and derivatives Subclass Indolines Intermediate Tree Nodes Not available Direct Parent Indolines Alternative Parents Ketals Benzenoids 1,3-dioxanes Secondary carboxylic acid amides Lactams Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aromatic heteropolycyclic compounds Substituents Dihydroindole - Ketal - Meta-dioxane - Benzenoid - Carboxamide group - Lactam - Secondary carboxylic acid amide - Acetal - Carboxylic acid derivative - Oxacycle - Azacycle - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Organooxygen compound - Hydrocarbon derivative - Carbonyl group - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as indolines. These are compounds containing an indole moiety, which consists of pyrrolidine ring fused to benzene to form 2,3-dihydroindole. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 39.44, Max Conc. mM: 100 Molecular Weight 394.400 g/mol XLogP3 0.500 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 0 Exact Mass 394.116 Da Monoisotopic Mass 394.116 Da Topological Polar Surface Area 95.100 Ų Heavy Atom Count 29 Formal Charge 0 Complexity 646.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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